MilliporeSigma
All Photos(3)

Documents

A9434

Sigma-Aldrich

Ammonium chloride

for molecular biology, suitable for cell culture, ≥99.5%

Sign Into View Organizational & Contract Pricing

Synonym(s):
Salmiac
Linear Formula:
NH4Cl
CAS Number:
Molecular Weight:
53.49
Beilstein:
4371014
EC Number:
MDL number:
eCl@ss:
38050207
PubChem Substance ID:
NACRES:
NA.31

grade

for molecular biology

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

Assay

≥99.5%

form

powder or crystals

technique(s)

cell culture | mammalian: suitable

mp

340 °C (subl.) (lit.)

anion traces

phosphate (PO43-): ≤2 ppm
sulfate (SO42-): ≤20 ppm

cation traces

Fe: ≤2 ppm
heavy metals (as Pb): ≤5 ppm

foreign activity

DNase, RNase, protease, none detected

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1120925413431107
Ammonium chloride for molecular biology, suitable for cell culture, ≥99.5%

Sigma-Aldrich

A9434

Ammonium chloride

-
Ammonium chloride puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, 99.5-100.5% (calc. to the dried substance)

Sigma-Aldrich

11209

Ammonium chloride

Essential Grade
Ammonium chloride 99.998% trace metals basis

Sigma-Aldrich

254134

Ammonium chloride

-
Ammonium chloride puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%

Sigma-Aldrich

31107

Ammonium chloride

Essential Grade
vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

assay

≥99.5%

assay

99.5-100.5% (calc. to the dried substance)

assay

99.998% trace metals basis

assay

≥99.5%

form

powder or crystals

form

solid

form

powder

form

crystalline powder

mp

340 °C (subl.) (lit.)

mp

340 °C (subl.) (lit.)

mp

340 °C (subl.) (lit.)

mp

340 °C (subl.) (lit.)

anion traces

phosphate (PO43-): ≤2 ppm, sulfate (SO42-): ≤20 ppm

anion traces

bromide (Br-): in accordance, iodide (I-): in accordance, sulfate (SO42-): ≤100 mg/kg

anion traces

-

anion traces

nitrate (NO3-): ≤5 mg/kg, phosphate (PO43-): ≤2 mg/kg, sulfate (SO42-): ≤20 mg/kg

Application

Ammonium chloride has been used:
  • as an inhibitor of endosome acidification in vero cells
  • as an autophagy inhibitor in vascular smooth muscle cell (VSMC)
  • in the depletion and lysis of erythrocytes in testis parenchyma homogenate

Biochem/physiol Actions

Ammonium chloride is one of the three principal components of the nitrogen cycle. Ammonium chloride administration promotes creatinine and urea clearance andinduces metabolic acidosis in mice. Excess of ammonium chloride inhibits Kreb′s pathway in brain and depletes ATP in astrocytes. Ammonium chloride inhibits acidification in the endosome-lysosome system. Ammonium chloride is a hemolysing agent used for the lysis of erythrocytes.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

Infectious bronchitis virus entry mainly depends on clathrin mediated endocytosis and requires classical endosomal/lysosomal system
Wang H, et al.
Virology, 528, 118-136 (2019)
Aqueous ammonia and ammonium chloride hydrates: Principal infrared spectra
Max JJ and Chapados C
Journal of Molecular Structure, 1046, 124-135 (2013)
Effect of ammonium chloride and dietary phosphorus in the azotaemic rat. I. Renal function and biochemical changes
Jara A, et al.
Nephrology, Dialysis, and Transplantation, 19(8), 1986-1992 (2004)
Nrf2 Activation Provides Atheroprotection in Diabetic Mice Through Concerted Upregulation of Antioxidant, Anti-inflammatory, and Autophagy Mechanisms
Lazaro I, et al.
Frontiers in Pharmacology, 9, 118-136 (2018)
Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells
Misinzo G, et al.
Journal of Virology, 82(3), 1128-1135 (2008)

Protocols

The GenElute Mammalian Genomic DNA Purification Kit Protocol describes the isolation of pure, high molecular weight DNA from a variety of mammalian sources.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service