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A9512

Sigma-Aldrich

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate

≥99% (TLC), solid, vasoconstrictor

Synonym(s):

L-(−)-Noradrenaline (+)-bitartrate salt monohydrate

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · C4H6O6 · H2O
CAS Number:
Molecular Weight:
337.28
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

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Product Name

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate, ≥99%, solid

Quality Level

assay

≥99%

form

solid

color

white

solubility

H2O: 46 mg/mL

SMILES string

O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1

InChI key

LNBCGLZYLJMGKP-LUDZCAPTSA-N

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1 of 4

This Item
N5785PHR38201468501
assay

≥99%

assay

-

assay

-

assay

-

form

solid

form

solid

form

-

form

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

-

solubility

H2O: 46 mg/mL

solubility

-

solubility

-

solubility

-

color

white

color

-

color

-

color

-

Application

L-(-)-Norepinephrine (+)-bitartrate salt monohydrate has been used:
  • to infuse dogs to form a intracellular lipid accumulation model[1]
  • to analyse the signaling involved in the up-regulation of monocarboxylate transporter 2 (MCT2) expression in cultured cortical neuron[2]
  • in neurochemical preparation to study the response of gram-negative and gram-positive bacteria to norepinephrine[3]
  • to study the roles of peripheral hormones on thyroid activity of turtles[4]

Biochem/physiol Actions

Norepinephrine bitartrate plays an important role in in vivo and in vitro development of pathogenic and indigenous bacteria.[3] It acts as a vasoconstrictor and adrenergic neurotransmitter.

Disclaimer

Light sensitive

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Roles of thyroid, adrenal and pancreatic hormones on thyroid activity of the soft-shelled turtles Lissemys punctata punctata Bonnoterre
Ray PP, et al.
Folia Biologica (Krakow.), 54(3-4), 93-102 (2006)
Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway
Chenal J and Pellerin L
Journal of Neurochemistry, 102(2), 389-397 (2007)
Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo
Szczepaniak LS, et al.
American Journal of Physiology. Endocrinology and Metabolism, 276(5), E977-E989 (1999)
Jonathan E Wingo et al.
Journal of applied physiology (Bethesda, Md. : 1985), 109(5), 1301-1306 (2010-08-14)
Sweat rate (SR) is reduced in locally cooled skin, which may result from decreased temperature and/or parallel reductions in skin blood flow. The purpose of this study was to test the hypotheses that decreased skin blood flow and decreased local
Stimulation of bacterial growth by heat-stable, norepinephrine-induced autoinducers
Freestone PPE, et al.
FEMS Microbiology Letters, 172(1), 53-60 (1999)

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