A9878

Sigma-Aldrich

4-Aminobenzoic acid

ReagentPlus®, ≥99%

Synonym(s):
Vitamin H1, Vitamin Bx, para-Aminobenzoic acid, PABA
Linear Formula:
H2NC6H4CO2H
CAS Number:
Molecular Weight:
137.14
Beilstein/REAXYS Number:
471605
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

biological source

synthetic (organic)

Quality Level

product line

ReagentPlus®

assay

≥99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis: suitable

mp

187-189 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless to faintly yellow

density

1.374 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)C(O)=O

InChI

1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)

InChI key

ALYNCZNDIQEVRV-UHFFFAOYSA-N

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Application

4-Aminobenzoic acid (4-ABA) can be used in the synthesis of:
  • Schiff bases based on 4-ABA with good antibacterial activity.
  • Co(II) and Mn(II) salts of 4-ABA supported on silica gel which in turn can be used as catalysts in oxidation of thiols to disulfides.
  • 4-amino-3-bromobenzoic acid.
  • Curing agent, N-(4-carboxyphenyl)trimellitimide (NCPT).

Packaging

5, 25, 100 g in glass bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

339.8 °F

Flash Point(C)

171 °C

Regioselective, photochemical bromination of aromatic compounds using N-bromosuccinimide.
Chhattise PK, et al.
Tetrahedron Letters, 49(1), 189-194 (2008)
Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid.
Parekh J, et al.
J. Serb. Chem. Soc., 70(10), 1155-1155 (2005)
Oxidation of thiols to disulfides by oxygen in presence of cobalt (II) and manganese (II) salts of 4-aminobenzoic acid supported on silica gel.
Hashemi MM and Karimi JZ
Monatshefte fur Chemie / Chemical Monthly, 135(1), 41-43 (2004)
Rosin-derived imide-diacids as epoxy curing agents for enhanced performance.
Liu X, et al
Bioresource Technology, 101(7), 2520-2524 (2010)
Robert B Campenot et al.
Nature protocols, 4(12), 1869-1887 (2009-12-17)
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