A9891
7-Amino-4-methylcoumarin
chromophore for enzyme substrates, fluorogenic, ≥98% (HPLC), powder
Synonym(s):
Coumarin 120
About This Item
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product name
7-Amino-4-methylcoumarin, Chromophore for substrates
Quality Level
description
chromophore for enzyme substrates
assay
≥98% (HPLC)
form
powder
mp
223-226 °C (lit.)
solubility
acetone: 10 mg/mL, clear, colorless to yellow
fluorescence
λex 365 nm; λem 440 nm in ethanol(lit.)
storage temp.
2-8°C
SMILES string
CC1=CC(=O)Oc2cc(N)ccc12
InChI
1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
InChI key
GLNDAGDHSLMOKX-UHFFFAOYSA-N
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Application
- to determine cathepsin B like- activity
- as a substrate for leucine aminopeptidase (LAP)
- in chymotryptic assay
- as a standard to detect the activation of caspase-3 during
- sanguinarine-induced damage
- protection by human DEAD-box DDX3
Biochem/physiol Actions
Preparation Note
Other Notes
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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