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A9920

Sigma-Aldrich

β-Alanine

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:
NH2CH2CH2COOH
CAS Number:
Molecular Weight:
89.09
Beilstein/REAXYS Number:
906793
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
39030936
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

assay

≥98% (TLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

color

white

mp

202 °C (dec.) (lit.)

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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General description

An N-blocked form of alanine.

Biochem/physiol Actions

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Ramin Artang et al.
The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)
Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate
Wilma Potze et al.
British journal of haematology, 163(5), 666-673 (2013-11-14)
There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these patients is rapidly emerging. Due to extensive haemostatic changes in patients with cirrhosis, careful monitoring of anticoagulant therapy may be
K M Gibson et al.
Journal of neurochemistry, 81(1), 71-79 (2002-06-18)
Metabolite profiling in succinate semialdehyde dehydrogenase (SSADH; Aldh5a1-/-) deficient mice previously revealed elevated gamma-hydroxybutyrate (GHB) and total GABA in urine and total brain and liver extracts. In this study, we extend our metabolic characterization of these mutant mice by documenting
Torben Bjerregaard Larsen et al.
The American journal of medicine, 127(4), 329-336 (2013-12-24)
Dabigatran may provide less protection against myocardial infarction than vitamin K antagonists (VKAs) in patients with atrial fibrillation. This may be particularly evident among "switchers" to dabigatran from VKA, as a result of discontinuation effects. We identified in nationwide Danish

Articles

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