AV100797

Anti-SOX9 Antibody

Name: Anti-SOX9 Antibody
Brand: SIGMA
Price: 490 USD

rabbit polyclonal

Synonym(s):

Anti-SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)

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100 μL

$490.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

A recombinant, preservative-free antibody is available for your target. Try ZRB5535

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

Key Documents

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Product Name

Anti-SOX9 antibody produced in rabbit, IgG fraction of antiserum

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

56 kDa

species reactivity

rabbit, goat, mouse, bovine, human, guinea pig, rat, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_000337

UniProt accession no.

P48436

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SOX9(6662)

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Show Differences

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This Item	SAB4502834	SAB4200450	AV38234
$Anti-SOX9 antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich AV100797 Anti-SOX9 antibody produced in rabbit	Sigma-Aldrich SAB4502834 Anti-SOX9 antibody produced in rabbit	$Anti-SOX11 (C-terminal) antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich SAB4200450 Anti-SOX11 (C-terminal) antibody produced in rabbit	Sigma-Aldrich AV38234 Anti-SOX4 antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum	antibody form affinity isolated antibody
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution

Immunogen

Synthetic peptide directed towards the N terminal region of human SOX9

Application

Anti-SOX9 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 μg/ml.

Biochem/physiol Actions

Sox9 is a transcription factor involved in a wide range of developmental processes. It is required for cartilage development, morphogenesis of face, testis differentiation and sex determination.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: PCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKG

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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related product

Product No.

Description

Pricing

ZRB5535

Anti-SOX-9 Antibody, clone 2B10, ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells

wgk

WGK 3

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

QC7136

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Sox9 function in craniofacial development and disease.

Young-Hoon Lee et al.

Genesis (New York, N.Y. : 2000), 49(4), 200-208 (2011-02-11)

The Sox family of transcriptional regulators has been implicated in the control of a broad array of developmental processes. One member of this family SOX9 was first identified as a candidate gene for campomelic dysplasia (CD), a human syndrome affecting

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds.

S Morais da Silva et al.

Nature genetics, 14(1), 62-68 (1996-09-01)

Heterozygous mutations in SOX9 lead to a human dwarfism syndrome, Campomelic dysplasia. Consistent with a role in sex determination, we find that Sox9 expression closely follows differentiation of Sertoli cells in the mouse testis, in experimental sex reversal when fetal

Sox9 is required for cartilage formation.

W Bi et al.

Nature genetics, 22(1), 85-89 (1999-05-13)

Chondrogenesis results in the formation of cartilages, initial skeletal elements that can serve as templates for endochondral bone formation. Cartilage formation begins with the condensation of mesenchyme cells followed by their differentiation into chondrocytes. Although much is known about the

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