Synthetic peptide directed towards the N terminal region of human CBFA2T3
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5′-region of the AML1 gene fused to the 3′-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Synthetic peptide located within the following region: QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPTAINGAPCTPN
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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