Skip to Content
MilliporeSigma
Get up to 22% off for Pi Day until 3/26.Save Now

B1532

Resorufin benzyl ether

CYP450 substrate, ≥98% (TLC), powder

Synonym(s):

7-Benzyloxy-3H-phenoxazin-3-one, 7-Benzyloxyresorufin, O7-Benzylresorufin

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

5 MG

$429.25

10 MG

$886.00

$429.25

List Price$505.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails

​

About This Item

Empirical Formula (Hill Notation):
C19H13NO3
CAS Number:
87687-02-3
Molecular Weight:
303.31
UNSPSC Code:
12352204
PubChem Substance ID:
24891597
NACRES:
NA.32
MDL number:
MFCD00171613

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Resorufin benzyl ether, CYP450 substrate

SMILES string

O=C1C=CC2=Nc3ccc(OCc4ccccc4)cc3OC2=C1

InChI

1S/C19H13NO3/c21-14-6-8-16-18(10-14)23-19-11-15(7-9-17(19)20-16)22-12-13-4-2-1-3-5-13/h1-11H,12H2

InChI key

XNZRYTITWLGTJS-UHFFFAOYSA-N

assay

≥98% (TLC)

form

powder

solubility

chloroform: 9.80-10.20 mg/mL, clear, orange

storage temp.

2-8°C

Quality Level

200

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
M1544E376346121
Resorufin benzyl ether CYP450 substrate

Sigma-Aldrich

B1532

Resorufin benzyl ether

Resorufin methyl ether

Sigma-Aldrich

M1544

Resorufin methyl ether

Resorufin ethyl ether ≥98% (TLC), powder

Sigma-Aldrich

E3763

Resorufin ethyl ether

Resorufin ethyl ether suitable for fluorescence, ≥95% (UV)

Sigma-Aldrich

46121

Resorufin ethyl ether

assay

≥98% (TLC)

assay

≥98.0% (HPLC)

assay

≥98% (TLC)

assay

≥95% (UV)

solubility

chloroform: 9.80-10.20 mg/mL, clear, orange

solubility

dichloromethane: 0.95-1.05 mg/mL, clear, orange to very deep orange

solubility

chloroform: 9.80-10.20 mg/mL, clear, orange

solubility

DMF: soluble, DMSO: soluble, alcohols: soluble

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

General description

Fluorimetric substrate for cytochrome P450-linked enzymes.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000300650
0000300650
0000235437
0000229250
0000229250

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nantana Nuchtavorn et al.
Analytica chimica acta, 1098, 86-93 (2020-01-18)
Cytochrome P450 (CYP450), and in particular CYP3A4, is the most abundantly expressed CYP450 isozyme implicated in many drug-drug and medicinal plant-drug interactions. Therefore, incorporation of CYP3A4 enzyme screening at an early stage of drug discovery is preferable in order to
R D Verschoyle et al.
The Journal of pharmacology and experimental therapeutics, 265(1), 386-391 (1993-04-01)
The O-dealkylation of pentoxyresorufin, a substrate for P450 2B1, was decreased in lung microsomes from rats dosed with O,O,S-trimethylphosphorodithioate, O,O,O-trimethylphosphorothioate, bromophos, fenitrothion, p-xylene and 2,4-dichloro-(6-phenylphonoxy)ethylamine. This activity was decreased by antibodies to P450 2B1 but unaffected by antibodies to P450
R Perrin et al.
Biochemical pharmacology, 40(9), 2145-2151 (1990-11-01)
The regional and subcellular distributions of rat brain cytochrome P450 and cytochrome P450-dependent activities were examined. Cytochrome P450 was found to be mainly localized in mitochondria in all the six cerebral regions studied. The activities of the isoforms mostly implicated
Y Q He et al.
Archives of biochemistry and biophysics, 335(1), 152-160 (1996-11-01)
Based on recent studies of single reciprocal mutants of cytochrome P450 2B4 and the highly related P450 2B5 at positions 114, 294, 363, and 367 [G. D. Szklarz, Y. Q. He, K. M. Kedzie, J. R. Halpert, and V. L.
Benzyloxyresorufin as a specific substrate for the major phenobarbital-inducible dog liver cytochrome P450 (P4502B11).
P A Klekotka et al.
Drug metabolism and disposition: the biological fate of chemicals, 23(12), 1434-1435 (1995-12-01)
View All Related Papers

Articles

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service