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All Photos(3)

B2133

Sigma-Aldrich

N-Benzoyl-Pro-Phe-Arg-p-nitroanilide hydrochloride

protease substrate

Synonym(s):
Anti-MCH6, Anti-PPP1R56
Empirical Formula (Hill Notation):
C33H38N8O6 · HCl
CAS Number:
Molecular Weight:
679.17
MDL number:
PubChem Substance ID:
NACRES:
NA.32

assay

≥97% (HPLC)

form

powder

solubility

methanol: 25 mg/mL

storage temp.

−20°C

SMILES string

Cl.NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C2CCCN2C(=O)c3ccccc3)C(=O)Nc4ccc(cc4)N(=O)=O

InChI

1S/C33H38N8O6.ClH/c34-33(35)36-19-7-13-26(29(42)37-24-15-17-25(18-16-24)41(46)47)38-30(43)27(21-22-9-3-1-4-10-22)39-31(44)28-14-8-20-40(28)32(45)23-11-5-2-6-12-23;/h1-6,9-12,15-18,26-28H,7-8,13-14,19-21H2,(H,37,42)(H,38,43)(H,39,44)(H4,34,35,36);1H

InChI key

OGYWLWIIQPDFPW-UHFFFAOYSA-N

Packaging

5 mg in glass bottle
25, 100 mg in poly bottle

Substrates

A chromogenic substrate for Agkistrodon contortrix thrombin-like enzyme and plasma kallikrein.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More documents

Quotes and Ordering

W Dick et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 19(6), 357-361 (1981-06-01)
A chromogenic assay for the determination of factor XII using the chromogenic substrate Chromozym PK was evaluated. The assay was linear in the range 10 U/l to more than 200 U/l. Using the assay, the normal range of factor XII
K Nishikawa et al.
Biochemical pharmacology, 43(6), 1361-1369 (1992-03-17)
Bradykinin (BK), an important mediator of allergic reactions and pain induction, is released by the activation of the plasma kallikrein-kinin (K-K) cascade. Neurotropin is a biological material obtained from inflamed rabbit skin inoculated with vaccinia virus and is widely used
G Claeson et al.
Haemostasis, 7(2-3), 62-68 (1978-01-01)
Chromogenic peptide substrates for serine proteases have been designed by using two approaches: (1) by using the natural substrate as a model and (2) by structure-activity correlations obtained through screening of a large number of tripeptides. Some recent examples, substrates
[Determination of factor XII and plasma prekallikrein with chromozym PK].
J Stürzebecher et al.
Zeitschrift fur medizinische Laboratoriumsdiagnostik, 23(5), 306-311 (1982-10-01)
A V Nieuw Amerongen et al.
Biochimica et biophysica acta, 786(3), 245-251 (1984-05-17)
The previously isolated female submandibular glycoprotein AM1 ( Nieuw Amerongen , A.V., Vreugdenhil , A.P. and Roukema , P.A. (1977) Biochim. Biophys. Acta 495, 324-335) has been shown to have hydrolytic activity using N-alpha-benzoyl-L-arginine ethylester (BAEE) and ChromozymR PK as

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