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B2517

6-Biopterin

≥97%

Synonym(s):

(1’R,2’S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin

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Pack SizeSKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$158.00
25 mg

Available to ship TODAYfromMILWAUKEE

$475.00
50 mg

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$786.00

About This Item

Empirical Formula (Hill Notation):
C9H11N5O3
CAS Number:
22150-76-1
Molecular Weight:
237.22
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
24891654
EC Number:
244-807-8
Beilstein/REAXYS Number:
87860
MDL number:
MFCD00036787
Form:
powder
Assay:
≥97%
Solubility:
1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow
Biological source:
synthetic

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biological source

synthetic

Quality Level

200

assay

≥97%

form

powder

solubility

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

storage temp.

2-8°C

SMILES string

C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1

InChI

1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1

InChI key

LHQIJBMDNUYRAM-DZSWIPIPSA-N

Application

6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 via q-BH2. Recent studies suggest that 6-Biopterin among other pteridines may be a useful non-invasive biomarker for cancer.

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This Item
3727219565SML0675
6-Biopterin ≥97%

Sigma-Aldrich

B2517

6-Biopterin

7,8-Dihydro-L-biopterin ≥94% (HPLC)

Sigma-Aldrich

37272

7,8-Dihydro-L-biopterin

(6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate ≥96% (HPLC)

Sigma-Aldrich

19565

(6S)-5,6,7,8-Tetrahydro-L-erythro-biopterin sulfate

α-Methylnorepinephrine ≥95% (HPLC)

Sigma-Aldrich

SML0675

α-Methylnorepinephrine

solubility

1 M NaOH: soluble-10 mg/mL, clear, colorless to light greenish-yellow

solubility

-

solubility

-

solubility

DMSO: 5 mg/mL, clear (warmed)

assay

≥97%

assay

≥94% (HPLC)

assay

≥96% (HPLC)

assay

≥95% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

biological source

synthetic

biological source

-

biological source

-

biological source

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

-

form

powder or crystals

form

powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8417
BCCL0760
BCCH9604
BCCD8434
BCBZ8817

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Eugenia Bifeld et al.
mSystems, 3(6) (2018-12-07)
The 90-kDa heat shock protein (HSP90) of eukaryotes is a highly abundant and essential chaperone required for the maturation of regulatory and signal proteins. In the protozoan parasite Leishmania donovani, causative agent of the fatal visceral leishmaniasis, HSP90 activity is
Suzanne V Saenko et al.
BMC biology, 11, 105-105 (2013-10-09)
Color traits in animals play crucial roles in thermoregulation, photoprotection, camouflage, and visual communication, and are amenable to objective quantification and modeling. However, the extensive variation in non-melanic pigments and structural colors in squamate reptiles has been largely disregarded. Here
Siew Ling Choy et al.
Scientific reports, 7(1), 9472-9472 (2017-08-27)
Intracellular pathogens belonging to the genus Leishmania have developed effective strategies that enable them to survive within host immune cells. Immunostimulatory compounds that counteract such immunological escape mechanisms represent promising treatment options for diseases. Here, we demonstrate that a lipopeptidephosphoglycan
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Global Trade Item Number

SKUGTIN
B2517-5MG04061833426869
B2517-50MG04061833045398
B2517-25MG04061833426852

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