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B3295

Sigma-Aldrich

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester

≥95% (TLC), powder

Synonym(s):

6-(Biotinamidocaproylamido)caproic acid N-hydroxysuccinimide ester, Biotin-X-X-NHS, N-Succinimidyl N-[6-(biotinylamino)caproyl]-6-aminocaproate

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About This Item

Empirical Formula (Hill Notation):
C26H41N5O7S
CAS Number:
Molecular Weight:
567.70
Beilstein/REAXYS Number:
8377428
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NC.07

Quality Level

assay

≥95% (TLC)

form

powder

solubility

DMF: 25 mg/mL

storage temp.

−20°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI

1S/C26H41N5O7S/c32-20(27-16-8-2-4-12-24(36)38-31-22(34)13-14-23(31)35)10-3-1-7-15-28-21(33)11-6-5-9-19-25-18(17-39-19)29-26(37)30-25/h18-19,25H,1-17H2,(H,27,32)(H,28,33)(H2,29,30,37)/t18-,19-,25-/m0/s1

InChI key

ATYCFNRXENKXSE-MHPIHPPYSA-N

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Application

Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester has been used in human IgM biotinylation.
Biotinylation reagent incorporating an extended 14-atom spacer can reduce steric hindrance in binding avidin or streptavidin to some biotinylated compounds and increase sensitivity for detection. Typically coupled to primary amine in the pH range 6.5-8.5.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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