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B3876

Sigma-Aldrich

BICINE

≥99% (titration)

Synonym(s):
N,N-Bis(2-hydroxyethyl)glycine
Empirical Formula (Hill Notation):
C6H13NO4
CAS Number:
Molecular Weight:
163.17
Beilstein:
1769362
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99% (titration)

form

powder or crystals

pH

3.5-5.0

useful pH range

7.6-9.0

pKa (25 °C)

8.3

solubility

water: 25 % (w/w), clear, colorless

application(s)

diagnostic assay manufacturing

storage temp.

room temp

SMILES string

OCCN(CCO)CC(O)=O

InChI

1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)

InChI key

FSVCELGFZIQNCK-UHFFFAOYSA-N

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This Item
T0377B8660RDD036
BICINE ≥99% (titration)

Sigma-Aldrich

B3876

BICINE

Tricine ≥99% (titration)

Sigma-Aldrich

T0377

Tricine

BICINE BioXtra, ≥99% (titration)

Sigma-Aldrich

B8660

BICINE

BICINE Redi-Dri™, ≥99%, free-flowing

Sigma-Aldrich

RDD036

BICINE

form

powder or crystals

form

crystalline powder

form

powder

form

-

pH

3.5-5.0

pH

-

pH

4.0-6.0 (1 M in H2O)

pH

-

solubility

water: 25 % (w/w), clear, colorless

solubility

water: 0.25 g/mL, clear, colorless

solubility

H2O: 1 M, clear, colorless

solubility

-

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

-

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

-

Application

Recommended buffer for low temperature biochemical work. Used in the preparation of stable substrate solution for serum guanase determination. Spacer in plasma protein fractionation with Sephadex® by isotachophoresis.

Legal Information

Sephadex is a registered trademark of Cytiva

replaced by

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
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Raewyn M Town et al.
The journal of physical chemistry. A, 112(12), 2563-2571 (2008-03-04)
The impact of ligand protonation on the complexation kinetics of higher-order complexes is quantitatively described. The theory is formulated on the basis of the usual situation for metal complex formation in aqueous systems in which the exchange of water for
Irradiation inactivation analysis of acetylcholinesterase and the effect of buffer salts.
D Parkinson et al.
Radiation research, 90(2), 252-259 (1982-05-01)
The myosin dimer: an intermediate in the self-assembly of the thick filament of vertebrate skeletal muscle.
J S Davis et al.
FEBS letters, 140(2), 293-297 (1982-04-19)
T A Churchill et al.
Transplantation, 65(4), 551-559 (1998-03-21)
This study was designed to investigate the effects of a modified University of Wisconsin (UW) solution supplemented with one of four buffering agents (histidine, bicine [N,N-bis(2-hydroxyethyl)glycine], tricine [N-tris(hydroxymethyl)methylglycine], and Tris) on liver metabolism during cold ischemic storage. Rat livers were
B M Altura et al.
British journal of pharmacology, 69(2), 207-214 (1980-06-01)
1 In vitro studies were undertaken on rat aortic strips and portal vein segments in order to determine whether or not several commonly used artificial buffers, i.e., tris(hydroxymethyl) aminomethane (Tris), N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid (HEPES), morpholine propanesulphonic acid (MOPS), N,N bis(2-hydroxyethyl) glycine

Protocols

Recycling Micro-Assay of β-NAD and β-NADH

Objective: To standardize a procedure for the recycling micro-assay of β-NAD and β-NADH

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