Bovine Serum Albumin

lyophilized powder, suitable for (for molecular biology), Non-acetylated

Albumin bovine serum, Bovine albumin, BSA
CAS Number:
EC Number:
MDL number:

Quality Level

biological source



for molecular biology


lyophilized powder



mol wt

~66 kDa

purified by

heat shock fractionation


glass bottle of


USA origin




water: soluble (50 mg/ml)


suitable for (for molecular biology)

UniProt accession no.

foreign activity

Alkaline Phosphatase free
Alkaline phosphatase and peroxidase, none detected
DNase free
DNase, RNase, and protease, none detected
Peroxidase free
Protease free
RNase free

storage temp.


Gene Information

bovine ... ALB(280717)

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Select the right albumin for your application with the Albumin Selection Guide

BSA has various uses in molecular biology, notably as an inert protein component to function as a stabilizer for proteins and enzymes of principal activity in solution. In such applications, BSA thus works, for example, to reduce risk of adhesion of the enzyme or other protein of interest to the reaction tube surface/wall or to the pipette surface. Thus during reactions, molecular biology grade BSA allows the enzyme or protein of interest to function properly, with minimal risk to the integrity of the protein or enzyme of interest.


25, 100 mg in glass bottle

Biochem/physiol Actions

Certain conformational and primary-sequence epitopes of BSA are suspected allergens in human beef and milk allergies.

Features and Benefits

This BSA product for molecular biology is tested for the following properties:
* Alkaline Phosphatase-free
* DNase-free / Exonuclease-free
* Nickase-free / Endonuclease-free
* Peroxidase-free
* Protease-free
* RNase-free

Preparation Note

Serum albumin may be referred to as Fraction V. This naming convention is taken from the original Cohn method of fractionating serum proteins using cold ethanol precipitation. Serum albumin was found in the fifth ethanol fraction using Cohn′s method. Since then, the term "Fraction V" has been used by some to describe serum albumin regardless of the method of preparation. Others have used this term to describe serum albumin purified by ethanol fractionation methods that have been highly modified since the original Cohn method was described. Sigma-Aldrich manufactures and distributes serum albumins purified from a variety of primary methods including the true Cohn fractionation method, modified ethanol fractionation methods, heat shock and chromatography. Additional purification steps may include crystallization or charcoal filtration.


11 - Combustible Solids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

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