B8556

Sigma-Aldrich

Hemocyanin from mollusk

buffered aqueous solution

Synonym(s):
Blue Carrier
CAS Number:
MDL number:
NACRES:
NA.56
Pricing and availability is not currently available.

Quality Level

biological source

Concholepas sp. (Concholepas concholepas )

form

buffered aqueous solution

application(s)

bioconjugation: suitable

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Hemocyanin is a carrier protein used in antibody production. It has been used to promote antibody production against haptins and peptides, in therepy for bladder carcinoma, and has a component in vaccines for cancer.
Blue Carrier is an oxygen-carrying protein isolated from the hemolymph of the mollusk Concholepas concholepas. It is highly immunogenic, useful as a carrier protein for the production of antibodies to small molecules. An example of the protocol is given in reference to production of antibodies to gizzerosine.

Biochem/physiol Actions

Highly soluble carrier protein used in antibody production

Physical form

100 mg in 0.5 mL of 0.15 M NaCl, 0.1 M sodium phosphate, pH 7.2

Legal Information

Blue Carrier is a registered trademark of Biosonda S.A.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in...
M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate...
Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging...
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.