BS-41601Z

GlycoProfile^™ EZGlyco^® O-Glycan Prep Kit

Chemical O-glycan Release

• UNSPSC Code: 12352204

Properties

• conjugate: (O-linked)
• technique(s): HPLC: suitable; mass spectrometry (MS): suitable

Description

General description

• The kit adopts a unique O-glycan releasing method “Eliminative Oximation” using a high reactive amine and an organic superbase.
• Applications include characterization of O-glycosylation of recombinant glycoproteins in upstream R&D, quality control and process control.
• What’s included:
  • Protocol
  • Glycan Release Reagent A
  • Glycan Release Reagent B
  • Glycan Capturing Beads
  • Filter Column, 2-Aminobezamide
  • Reducing Reagent
  • Cleanup Column

Application

• Useful for release and labeling of O-linked glycans from glycoproteins for Glycomics by Mass Spec, capillary electrophoresis, HPLC or other analysis methods.
• O-glycan biomarker discovery and screening in biological samples such as mucins, serum and exosomes
• O-glycan analysis of functional foods such as dairy products

Features and Benefits

O-Glycan sample prep in 5 hours

High recovery

Minimize "peeling"

Easy and safe operation

Legal Information

EZGlyco is a registered trademark of SUMITOMO BAKELITE CO., LTD.

GlycoProfile is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS02,GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H261,H290,H301,H314,H317,H335,H351,H373,H410
• pcodes: P231 + P232 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 3 - Water-react 2
• target_organs: Blood, Respiratory system
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3