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C0128

Sigma-Aldrich

α-Chloralose

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Synonym(s):
1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose, Anhydro-D-glucochloral, Chloralose
Empirical Formula (Hill Notation):
C8H11Cl3O6
CAS Number:
Molecular Weight:
309.53
Beilstein:
85418
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

form

powder

Quality Level

impurities

≤20% β-anomer

color

white to off-white

solubility

ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow (or yellow-brown)

SMILES string

OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

InChI

1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1

InChI key

OJYGBLRPYBAHRT-IPQSZEQASA-N

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This Item
N137763620E1895
α-Chloralose

Sigma-Aldrich

C0128

α-Chloralose

Erlose

Sigma-Aldrich

E1895

Erlose

impurities

≤20% β-anomer

impurities

-

impurities

-

impurities

≤12.5% water (Karl Fischer)

color

white to off-white

color

-

color

colorless to white

color

white to off-white

solubility

ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow (or yellow-brown)

solubility

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

200

Application

α-Chloralose has been used as anesthetic in surgical preparations.

Biochem/physiol Actions

α-Chloralose is used as an immobilizing agent. It is mostly used in studies, which involves autonomic reflexes. α-Chloralose is a sedative hypnotic. It has high significance as anesthetic for laboratory animals.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Preparation of water-soluble compounds by covalent attachment of solubilizing moieties
The Practice of Medicinal Chemistry, 767-785 (2008)
Activation of serotonergic neurons in the medullary caudal raphe shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 102(8), 1007-1018 (2017)
Preanesthesia, anesthesia, analgesia, and euthanasia
Laboratory Animal Medicine, 1135-1200 (2015)
Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 101(7), 946-961 (2016)
Vertebrate pest control chemicals and their use in urban and rural environments
Hayes' Handbook of Pesticide Toxicology, 271-284 (2010)

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