C0399

Cromolyn sodium salt

≥95%

• Synonym(s): Cromoglycate, Cromoglycic acid
• Linear Formula: C₂₃H₁₄O₁₁Na₂
• CAS Number: 15826-37-6
• Molecular Weight: 512.33
• EC Number: 239-926-7
• MDL number: MFCD00057744
• PubChem Substance ID: 24892251
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥95%
• form: powder
• originator: Sanofi Aventis
• SMILES string: [Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O
• InChI: 1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;
• InChI key: UXMUBZWVLQEMRB-UHFFFAOYSA-N

Description

General description

Cromolyn sodium is a mast stabilizer, which is used to treat allergies. It is a bischromone and functions as a non-steroidal anti-inflammatory drug. It inhibits the release of histamines from mast cells.

Application

Cromolyn sodium salt has been used to block mast cell activation and to inhibit histamine secretion from rodent peritoneal mast cells. It has also been used to stabilize mast cells.

Biochem/physiol Actions

Cromolyn blocks the release of histamine and other pro-inflammatory mediators from mast cells.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves