MilliporeSigma
All Photos(1)

C0608

Sigma-Aldrich

Z-Leu-Leu-Leu-7-amido-4-methylcoumarin

≥95% (HPLC and TLC), solid

Synonym(s):
Cbz-Leu-Leu-Leu-AMC, Z-LLL-AMC
Empirical Formula (Hill Notation):
C36H48N4O7
Molecular Weight:
648.79
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥95% (HPLC and TLC)

form

solid

solubility

DMSO: soluble

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C36H48N4O7/c1-21(2)15-28(33(42)37-26-13-14-27-24(7)18-32(41)47-31(27)19-26)38-34(43)29(16-22(3)4)39-35(44)30(17-23(5)6)40-36(45)46-20-25-11-9-8-10-12-25/h8-14,18-19,21-23,28-30H,15-17,20H2,1-7H3,(H,37,42)(H,38,43)(H,39,44)(H,40,45)/t28-,29-,30-/m0/s1

InChI key

MBZJQSNQQJWUBH-DTXPUJKBSA-N

Amino Acid Sequence

Z-Leu-Leu-Leu-AMC

General description

Manufactured for Sigma by Boston Biochem., Inc.

Biochem/physiol Actions

Fluorogenic substrate for the measurement of the peptidase activity of the 20S proteasome.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service