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Key Documents

C0856

Sigma-Aldrich

C7BzO

Synonym(s):

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H37NO4S
Molecular Weight:
399.59
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.56

description

zwitterionic

assay

≥95.0% (HPLC)

form

solid

mol wt

399.59 Da (anhydrous)

aggregation number

≤25

technique(s)

dialysis: suitable
electrophoresis: suitable
protein quantification: suitable

SMILES string

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

General description

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.

Application

C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.

Other Notes

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Pigeon pea (Cajanus cajan (L.) Millspaugh) is cultivated widely in semiarid agricultural regions in over 90 countries around the world. This important legume can enter into symbiotic associations with a wide range of rhizobia including Bradyrhizobium and fast-growing rhizobia. In
Hari B Krishnan et al.
Proteomics, 9(11), 3174-3188 (2009-06-16)
2-D analysis of plant proteomes containing thousands of proteins has limited dynamic resolution because only abundant proteins can be detected. Proteomic assessment of the non-abundant proteins within seeds is difficult when 60-80% is storage proteins. Resolution can be improved through
Evaluation of nonionic and zwitterionic detergents as membrane protein solubilizers in two-dimensional electrophoresis
Luche S, et al.
Proteomics, 3(3), 249-253 (2003)

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