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C1254

Sigma-Aldrich

Sodium cholate hydrate

from bovine and/or ovine bile, ≥99%

Synonym(s):
3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO5 · xH2O
CAS Number:
Molecular Weight:
430.55 (anhydrous basis)
Beilstein:
3582354
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

bovine and/or ovine bile

Quality Level

description

anionic

assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

technique(s)

DNA purification: suitable
RNA purification: suitable
western blot: suitable

CMC

9-15 mM (20-25°C)

HLB

18

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

InChI key

MUVVIYFKOVLQHL-RCVKHMDESA-M

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General description

Sodium cholate hydrate is a bio-surfactant which can be used as a reducing reagent in aqueous solution.

Application

Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

Packaging

10, 25, 100, 500 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

Biochem/physiol Actions

Bile Salt

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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