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C1276

Sigma-Aldrich

L-Cysteine hydrochloride

anhydrous, ≥98% (TLC)

Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
Molecular Weight:
157.62
Beilstein:
3560277
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

grade

anhydrous

assay

≥98% (TLC)

form

powder

technique(s)

UHPLC: suitable

color

white

mp

174.1-174.7 °C

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

Cl[H].N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1

InChI key

IFQSXNOEEPCSLW-DKWTVANSSA-N

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Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.

Biochem/physiol Actions

NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.
Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Richard S. Lord, J. Alexander Bralley
Laboratory Evaluations for Integrative and Functional Medicine (2008)
Independent Effects of ?-Aminobutyric Acid Transaminase (GABAT) on Metabolic and Sleep Homeostasis
Sarah E. Maguire
The Journal of Biological Chemistry, 290 (2015)
Isolation of intact astrocytes from the optic nerve head of adult mice
Hee Joo Choi
Experimental Eye Research, 137, 103-110 (2015)
Justin Komguep Nono et al.
Frontiers in immunology, 11, 798-798 (2020-05-28)
Alveolar echinococcosis (AE), caused by the metacestode larval stage of the fox-tapeworm Echinococcus multilocularis, is a chronic zoonosis associated with significant modulation of the host immune response. A role of regulatory T-cells (Treg) in generating an immunosuppressive environment around the
Marc Y Fink et al.
Current protocols in microbiology, 57(1), e102-e102 (2020-06-10)
Giardia lamblia is a protozoan parasite that is found ubiquitously throughout the world and is a major contributor to diarrheal disease. Giardia exhibits a biphasic lifestyle existing as either a dormant cyst or a vegetative trophozoite. Infections are typically initiated

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