C1276

L-Cysteine hydrochloride

anhydrous, ≥98% (TLC)

• Synonym(s): (2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride
• Linear Formula: HSCH₂CH(NH₂)COOH · HCl
• CAS Number: 52-89-1
• Molecular Weight: 157.62
• Beilstein: 3560277
• EC Number: 200-157-7
• MDL number: MFCD00064553
• PubChem Substance ID: 24892395
• NACRES: NA.32

Properties

• grade: anhydrous
• Quality Level: 100
• Assay: ≥98% (TLC)
• form: powder
• technique(s): UHPLC: suitable
• color: white
• mp: 174.1-174.7 °C
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: Cl[H].N[C@@H](CS)C(O)=O
• InChI: 1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1
• InChI key: IFQSXNOEEPCSLW-DKWTVANSSA-N
• Gene Information: human ... AMPA 1(2890) , GRIA2(2891) , GRIA3(2892) , GRIA4(2893) , GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907) ; mouse ... AMPA 1(14799) , GRIA2(14800) , GRIA3(53623) , GRIA4(14802) , GRIN1(14810) , GRIN2A(14811) , GRIN2B(14812) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168) ; rat ... AMPA 1(50592) , GRIA2(29627) , GRIA3(29628) , GRIA4(29629) , GRIN1(24408) , GRIN2A(24409) , GRIN2B(24410) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

Description

Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.

Biochem/physiol Actions

Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.

NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves