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C2278

Sigma-Aldrich

CAPSO

≥99% anhydrous basis (titration)

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Synonym(s):
3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid
Empirical Formula (Hill Notation):
C9H19NO4S
CAS Number:
Molecular Weight:
237.32
Beilstein/REAXYS Number:
5939234
MDL number:
PubChem Substance ID:
NACRES:
NA.25

assay

≥99% anhydrous basis (titration)

form

crystalline powder

pH

2.5-4.0

useful pH range

8.9-10.3

pKa (25 °C)

9.6

solubility

water: 0.111 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

OC(CNC1CCCCC1)CS(O)(=O)=O

InChI

1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14)

InChI key

INEWUCPYEUEQTN-UHFFFAOYSA-N

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1 of 4

This Item
C4695C3649C2632
vibrant-m

C2278

CAPSO

-
vibrant-m

C4695

CHAPSO

Premium Grade
vibrant-m

C3649

CHAPSO

-
vibrant-m

C2632

CAPS

-
assay

≥99% anhydrous basis (titration)

assay

≥98.0% (TLC)

assay

≥98%

assay

≥99%

pH

2.5-4.0

pH

-

pH

-

pH

3.0-7.0

application(s)

diagnostic assay manufacturing

application(s)

-

application(s)

-

application(s)

diagnostic assay manufacturing

solubility

water: 0.111 g/mL, clear, colorless

solubility

H2O: 0.1 M, clear, colorless

solubility

-

solubility

H2O: soluble 15g + 85 mL, clear, colorless

form

crystalline powder

form

powder

form

powder

form

crystalline powder

General description

CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.

Application

CAPSO was used as biological buffer in the following studies:
  • To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
  • Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes. I
  • Preparation of planar bilayer lipid membranes.
It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Customers Also Viewed

Slide 1 of 2

1 of 2

H Stender et al.
Applied and environmental microbiology, 67(1), 142-147 (2001-01-03)
A new chemiluminescent in situ hybridization (CISH) method provides simultaneous detection, identification, and enumeration of culturable Escherichia coli cells in 100 ml of municipal water within one working day. Following filtration and 5 h of growth on tryptic soy agar
Second dissociation constants of 3-(cyclohexylamino)-1-propanesulfonic acid (CAPS) and 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid (CAPSO) from the temperatures 278.15 K to 328.15 K.
Roy RN, et al.
The Journal of Chemical Thermodynamics, 29(7), 749-756 (1997)
P I Bauer et al.
The Biochemical journal, 270(1), 17-26 (1990-08-15)
The macromolecular self-association of ADP-ribosyltransferase protein in solution was studied by several experimental techniques: quantitative gel filtration, electrophoretic analyses in non-denaturing gels, and cross-linking the enzyme protein with glutaraldehyde, dimethyl pimelimidate, dimethyl suberimidate, dimethyl 3,3'-dithiobisproprionimidate and tetranitromethane. The self-association of
Evaluation of leaching protocols for testing of high-carbon coal fly ash-soil mixtures.
Becker J, et al.
Journal of Environmental Engineering (New York, N.Y.), 139(5), 642-653 (2012)
Andreas Missner et al.
The Journal of biological chemistry, 283(37), 25340-25347 (2008-07-12)
Several membrane channels, like aquaporin-1 (AQP1) and the RhAG protein of the rhesus complex, were hypothesized to be of physiological relevance for CO(2) transport. However, the underlying assumption that the lipid matrix imposes a significant barrier to CO(2) diffusion was

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