C3915
Colchicine
BioReagent, suitable for plant cell culture, ≥95% (HPLC)
Recommended Products
product line
BioReagent
Assay
≥95% (HPLC)
form
powder
technique(s)
cell culture | plant: suitable
mp
150-160 °C (dec.) (lit.)
application(s)
agriculture
SMILES string
COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O
InChI
1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChI key
IAKHMKGGTNLKSZ-INIZCTEOSA-N
Gene Information
human ... ABCB1(5243) , CYP3A4(1576) , TUBA1A(7846) , TUBA1B(10376) , TUBA1C(84790) , TUBA3C(7278) , TUBA3E(112714) , TUBA4A(7277) , TUBB(203068) , TUBB1(81027) , TUBB2A(7280) , TUBB2B(347733) , TUBB3(10381) , TUBB4A(10382) , TUBB4B(10383) , TUBB6(84617) , TUBB8(347688)
mouse ... Abcb1a(18671) , Abcb1b(18669)
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This Item | PHR1764 | C9754 | PHL89610 |
|---|---|---|---|
| assay ≥95% (HPLC) | assay - | assay ≥95% (HPLC) | assay ≥95.0% (HPLC) |
| form powder | form - | form powder | form - |
| technique(s) cell culture | plant: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) - | technique(s) - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level - |
| product line BioReagent | product line - | product line - | product line phyproof® Reference Substance |
| mp 150-160 °C (dec.) (lit.) | mp 150-160 °C (dec.) (lit.) | mp 150-160 °C (dec.) (lit.) | mp 150-160 °C (dec.) (lit.) |
General description
Application
- as an inhibitor of tubulin polymerization in bone-marrow-derived macrophages
- for the inhibition of in vitro neurite outgrowth in human neuronal cells
- as microtubule destabilizer to induce peripheral neuropathy in induced pluripotent stem cell derived neurons (iPSC-Neurons)
Biochem/physiol Actions
Preparation Note
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Muta. 1B
Storage Class Code
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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