C4119

Sigma-Aldrich

Anti-CSNK2B (36-50) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):
Anti-CK2B, Anti-CK2N, Anti-Casein kinase 2, β polypeptide (Homo sapiens), Anti-G5A, Anti-CSK2B
Pricing and availability is not currently available.

biological source

rabbit

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~24 kDa

species reactivity

human

application(s)

western blot: 1:500-1:2,000

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CSNK2B(1460)

General description

Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is implicated in diverse cellular processes, including cell cycle control, apoptosis, and circadian rhythm.

Immunogen

synthetic peptide corresponding to amino acids 36-50 of human CSNK2B.

Application

Anti-CSNK2B (36-50) antibody is suitable for western blot at a dilution of 1:500-1:2,000
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit
sigma.com/htcb-if.

Biochem/physiol Actions

CSNK2B participates in Wnt signaling. It plays a intricate role in regulating the basal catalytic activity of the alpha subunit.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

2

D M Keller et al.
Molecular cell, 7(2), 283-292 (2001-03-10)
Phosphorylation of the human p53 protein at Ser-392 has been shown to be responsive to UV but not gamma irradiation. Here we describe identification and purification of a mammalian UV-activated protein kinase complex that phosphorylates Ser-392 of p53 in vitro....

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