C4330

Sigma-Aldrich

Casein Kinase II-β fragment 198-215

≥95% (HPLC)

Empirical Formula (Hill Notation):
C90H153N27O26
Molecular Weight:
2029.34
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

assay

≥95% (HPLC)

storage temp.

−20°C

SMILES string

CCC@H(C)C@H(NC(=O)C@@H(NC(=O)C@H(CCCCN)NC(=O)C@@H(NC(=O)C@@H1CCCN1C(=O)C@H(CO)NC(=O)C@H(CCCCN)NC(=O)C@H(Cc2ccccc2)NC(=O)C@H(CC(N)=O)NC(=O)C@H(CO)NC(=O)C@H(C)NC(=O)C@H(C)NC(=O)C@H(CCC(N)=O)NC(=O)C@H(CC(C)C)NC(=O)C@H(CCC(N)=O)NC(=O)C@H(CC(C)C)NC(=O)C@@H(N)CCC(N)=O)C(C)C)C@@H(C)O)C(=O)NC@@H(CCCNC(N)=N)C(O)=O

InChI

1S/C90H153N27O26/c1-12-47(8)70(86(139)107-57(89(142)143)26-20-36-100-90(98)99)115-87(140)71(50(11)120)116-78(131)54(25-17-19-35-92)106-85(138)69(46(6)7)114-84(137)64-27-21-37-117(64)88(141)63(43-119)113-76(129)53(24-16-18-34-91)103-81(134)60(40-51-22-14-13-15-23-51)110-82(135)61(41-68(97)124)111-83(136)62(42-118)112-73(126)49(10)101-72(125)48(9)102-75(128)55(29-32-66(95)122)104-80(133)59(39-45(4)5)109-77(130)56(30-33-67(96)123)105-79(132)58(38-44(2)3)108-74(127)52(93)28-31-65(94)121/h13-15,22-23,44-50,52-64,69-71,118-120H,12,16-21,24-43,91-93H2,1-11H3,(H2,94,121)(H2,95,122)(H2,96,123)(H2,97,124)(H,101,125)(H,102,128)(H,103,134)(H,104,133)(H,105,132)(H,106,138)(H,107,139)(H,108,127)(H,109,130)(H,110,135)(H,111,136)(H,112,126)(H,113,129)(H,114,137)(H,115,140)(H,116,131)(H,142,143)(H4,98,99,100)/t47-,48-,49-,50+,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,69-,70-,71-/m0/s1

InChI key

OMUTVGVKPXPHPX-TWWSAIDSSA-N

Gene Information

human ... CSNK2B(1460)

Amino Acid Sequence

Gln-Leu-Gln-Leu-Gln-Ala-Ala-Ser-Asn-Phe-Lys-Ser-Pro-Val-Lys-Thr-Ile-Arg

Biochem/physiol Actions

Cdc2 substrate and competitive inhibitor of apoptosis. Sequence contains CK II autophosphorylation site plus p34cdc2 consensus phosphorylation site Ser209.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
L Shi et al.
Science (New York, N.Y.), 263(5150), 1143-1145 (1994-02-25)
Activation of the serine-threonine kinase p34cdc2 at an inappropriate time during the cell cycle leads to cell death that resembles apoptosis. Premature activation of p34cdc2 was shown to be required for apoptosis induced by a lymphocyte granule protease. The kinase...
D W Litchfield et al.
The Journal of biological chemistry, 266(30), 20380-20389 (1991-10-25)
To examine the phosphorylation of casein kinase II in cells, the enzyme was isolated by immunoprecipitation from metabolically labeled human epidermal carcinoma A431 cells using polyclonal antipeptide antibodies specific for either the alpha subunit or the beta subunit of the...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.