CACNA2D1 (calcium channel, voltage-dependent, α2/δ subunit 1) is a member of a family of GPI-anchored voltage-gated calcium channels (VGCCs)-associated subunits called α2δ. VGCC are composed of three types of subunits- pore-forming α1 and auxiliary β and α2δ subunits.
synthetic peptide corresponding to amino acids 1-15 of α2 subunit (amino acids 27-41 of rabbit α2/δ−1 precursor).
Anti-Calcium Channel (α2/δ-1 Subunit) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
CACNA2D1 (calcium channel, voltage-dependent, α2/δsubunit 1) is a type of α2δs, which are involved in the synaptic neurotransmitter release as they are concentrated at the synapses. They have a chaperone-like activity in non-neuronal cells. This protein acts as a target for gabapentin, which is a neuropathic analgesic. Mutations in this gene, in humans result in short QT syndrome (SQTS).
L-type of Voltage-gated Ca2+ Channel.
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.
Reconstitute the 0.05 mL vial with 50 μL deionized water. Reconstitute the 0.2 mL vial with 0.2 mL deionized water. After reconstitution, the antibody concentration is ~0.8 mg/mL.
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