MilliporeSigma
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C5108

Sigma-Aldrich

Cathepsin G from human sputum

≥0.2 units/mg protein, salt-free, lyophilized powder

CAS Number:
Enzyme Commission number:
MDL number:
NACRES:
NA.32

Quality Level

biological source

human sputum

form

salt-free, lyophilized powder

specific activity

≥0.2 units/mg protein

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... CTSG(1511)

Biochem/physiol Actions

Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.

Certificate of Analysis

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Certificate of Origin

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More Documents

Quotes and Ordering

Dawid Dębowski et al.
Peptides, 35(2), 276-284 (2012-04-21)
A series of linear and cyclic fragments and analogs of two peptides (OGTI and HV-BBI) isolated from skin secretions of frogs were synthesized by the solid-phase method. Their inhibitory activity against several serine proteinases: bovine β-trypsin, bovine α-chymotypsin, human leukocyte
E D Son et al.
Dermatology (Basel, Switzerland), 224(4), 352-360 (2012-07-05)
Cathepsin G, a serine protease that is activated by ultraviolet (UV) radiation, increases matrix metalloproteinase-1 (MMP-1) expression in fibroblasts through fibronectin (Fn) fragmentation and promotes the conversion of proMMP-1 to active MMP-1. This study investigated whether [2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-phosphonic acid (KPA), a
Prasad Tongaonkar et al.
PloS one, 7(3), e32469-e32469 (2012-03-27)
The azurophilic granules of human neutrophils contain four α-defensins called human neutrophil peptides (HNPs 1-4). HNPs are tridisulfide-linked antimicrobial peptides involved in the intracellular killing of organisms phagocytosed by neutrophils. The peptides are produced as inactive precursors (proHNPs) which are
Emma Lefrançais et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(5), 1673-1678 (2012-02-07)
Interleukin-33 (IL-33) (NF-HEV) is a chromatin-associated nuclear cytokine from the IL-1 family, which has been linked to important diseases, including asthma, rheumatoid arthritis, ulcerative colitis, and cardiovascular diseases. IL-33 signals through the ST2 receptor and drives cytokine production in type
A Siltari et al.
Arzneimittel-Forschung, 62(10), 477-481 (2012-08-25)
In the fermentation of milk by certain lactic acid bacteria, casein is degraded into bioactive tripeptides shown to lower blood pressure in experimental animal models and in mildly hypertensive humans. This effect is suggested to result mainly in inhibition of

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