C6594

Monoclonal Anti-c-Myc−Cy3^™ antibody produced in mouse

clone 9E10, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-c-Myc
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: CY3 conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 9E10, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue
• UniProt accession no.: P01106
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: human ... MYC(4609)

Description

General description

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa.

Immunogen

synthetic peptide of the human p62^c-Myc protein.

Application

Monoclonal Anti-c-MycCy3^™ antibody produced in mouse has been used in:

• western blotting
• immunocytochemistry
• Immunofluorescence

Biochem/physiol Actions

The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation.

Physical form

Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.

Legal Information

Cy3 is a trademark of Cytiva

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves