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C6719

Croton oil

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CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
MDL number:

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biological source

plant (Croton tiglium L)

form

viscous liquid

density

0.94 g/mL at 25 °C (lit.)

functional group

ester

lipid type

oils

shipped in

ambient

storage temp.

room temp

Quality Level

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This Item
C7767P2144C8267
biological source

plant (Croton tiglium L)

biological source

plant (Gossypium hirsutum L.)

biological source

peanut oil

biological source

maize

functional group

ester

functional group

-

functional group

oleic acid

functional group

ester

form

viscous liquid

form

liquid

form

liquid

form

liquid

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

density

0.94 g/mL at 25 °C (lit.)

density

0.92 g/mL at 25 °C (lit.)

density

0.91 g/mL at 25 °C (lit.)

density

0.9 g/mL at 25 °C (lit.)

General description

Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature.[1] Croton oil has a strong irritant property[1] and is used along with phenol in some chemical peels.[2] It also has a tumor promoting ability.[3]
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma.[4] Croton oil functions as a skin peeling agent.[5]

Application

Croton oil has been used to induce acute skin inflammation.[6]
Croton oil has been used to induce inflammation in mouse ears.[7][6][8]

Other Notes

Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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The inhibition of croton oil-promoted mouse skin tumorigenesis by steroid hormones
Belman S and Troll W
Cancer Research, 32(3), 450-454 (1972)
An examination of the phenol-croton oil peel: Part I. Dissecting the formula
Hetter GP
Plastic and Reconstructive Surgery, 105(1), 227-239 (2000)
Croton oil peels
Bensimon RH
Aesthetic Surgery Journal / The American Society for Aesthetic Plastic Surgery, 28(1), 33-45 (2008)
Phillip R Langsdon et al.
Facial plastic surgery : FPS, 28(1), 116-125 (2012-03-16)
Chemexfoliation is an excellent method to reduce facial rhytids. For 25 years, we have used the traditional formula as described by T. J. Baker but with a moist healing technique rather than a tape mask. We have found the peel
Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies
Komatsu N, et al.
Journal of Immunological Methods, 331(1-2), 82-93 (2008)

Questions

  1. What’s the origin of this croton tigliun oil?

    1 answer
    1. The product is extracted from Croton tiglium, a plant commonly known as purging croton. Although the country of origin may change, the material typically originates from China. Please see the link below to review a sample Certificate of Origin:
      https://www.sigmaaldrich.com/US/en/coo/undefined/C6719/MKBK0847V

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