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C7039
Cefotaxime sodium salt
powder or crystals, suitable for plant cell culture, BioReagent
Synonym(s):
Cefotaxim sodium salt
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100 MG
$66.40
500 MG
$200.00
1 G
$326.00
5 G
$1,280.00
10 G
$1,960.00
About This Item
Empirical Formula (Hill Notation):
C16H16N5NaO7S2
CAS Number:
Molecular Weight:
477.45
NACRES:
NA.72
PubChem Substance ID:
UNSPSC Code:
10171502
EC Number:
264-915-9
MDL number:
Beilstein/REAXYS Number:
5711411
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Product Name
Cefotaxime sodium salt, suitable for plant cell culture, BioReagent, powder or crystals
InChI key
AZZMGZXNTDTSME-JUZDKLSSSA-M
InChI
1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
SMILES string
[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
product line
BioReagent
form
powder or crystals
technique(s)
cell culture | plant: suitable
color
off-white to pale yellow
solubility
H2O: 10% ( )
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
application(s)
agriculture
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
Quality Level
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1 of 4
This Item | C7912 | C0685000 | Y0000506 |
|---|---|---|---|
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - |
| technique(s) cell culture | plant: suitable | technique(s) - | technique(s) - | technique(s) - |
| mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action - | mode of action - |
| product line BioReagent | product line - | product line - | product line - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| form powder or crystals | form powder | form - | form - |
Application
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria.[3] In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.[4]
Mode of Action: Inhibits bacterial cell wall synthesis.
General description
Chemical structure: ß-lactam
Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Urinary Tract Infection in Children and Antimicrobial Resistance Pattern: Children UTI and Antibiotic Resistance (2019)
Valeria Di Dato et al.
Scientific reports, 9(1), 9893-9893 (2019-07-11)
Diatoms are phytoplankton eukaryotic microalgae that are widely distributed in the world's oceans and are responsible for 20-25% of total carbon fixation on the planet. Using transcriptome sequencing here we show for the first time that the ubiquitous diatom Thalassiosira
Bacterial nanoscale cultures for phenotypic multiplexed antibiotic susceptibility testing
Weibull E, et al.
Journal of Clinical Microbiology, 52(9), 3310-3317 (2014)
Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use.
AA C, et al.
Drugs (1983)
Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri
Hirth M, et al.
Metabolomics, 13(9), 68-68 (2017)
Protocols
Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.
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