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C7252

Sigma-Aldrich

D-(+)-Cellobiose

≥98% (HPLC)

Synonym(s):

β-D-Glc-(1→4)-D-Glc, 4-O-β-D-Glucopyranosyl-D-glucose

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein/REAXYS Number:
93795
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

plant

Quality Level

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 34±1, c = 10% (w/v) in water

technique(s)

HPLC: suitable

color

beige

mp

239 °C (dec.) (lit.)

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8+,9-,10+,11+,12-/m0/s1

InChI key

DKXNBNKWCZZMJT-WELRSGGNSA-N

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General description

Cellobiose, a disaccharide, is made up of two d-glucose molecules linked by a β-1,4-glycosidic bond. This reducing sugar can mutarotate and is produced by hydrolysis of cellulose.

Application

D-(+)-Cellobiose has been used:
  • as a component in test sugar solution for cellobiose-mannitol permeability test
  • in the preparation of lyophilization solutions to study its ability to protect lyophilized β-galactosidase from enzymatic activity loss and secondary structure changes during storage
  • as a fermentation/growth substrate to grow Clostridium thermocellum to study its impacts on the qualitative and quantitative changes in cellulosome composition

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Mireia Lopez-Siles et al.
Applied and environmental microbiology, 78(2), 420-428 (2011-11-22)
Faecalibacterium prausnitzii is one of the most abundant commensal bacteria in the healthy human large intestine, but information on genetic diversity and substrate utilization is limited. Here, we examine the phylogeny, phenotypic characteristics, and influence of gut environmental factors on
Shuen Hon et al.
Metabolic engineering communications, 3, 120-129 (2016-04-22)
Clostridium thermocellum is a promising candidate for ethanol production from cellulosic biomass, but requires metabolic engineering to improve ethanol yield. A key gene in the ethanol production pathway is the bifunctional aldehyde and alcohol dehydrogenase, adhE. To explore the effects
David Scholz et al.
ChemSusChem, 11(13), 2189-2201 (2018-05-08)
The deactivation pathways of sulfonated carbon catalysts prepared from different carbons were studied during the aqueous-phase hydrolysis of cellobiose under continuous-flow conditions. The sulfonation of carbon materials with a low degree of graphitization introduced sulfonic acid groups that are partially
Linchao Zhou et al.
Royal Society open science, 5(6), 171529-171529 (2018-08-16)
Removing alkali-soluble lignin using extractive ammonia (EA) pretreatment of corn stover (CS) is known to improve biomass conversion efficiency during enzymatic hydrolysis. In this study, we investigated the effect of alkali-soluble lignin on six purified core glycosyl hydrolases and their
Babu Raman et al.
PloS one, 4(4), e5271-e5271 (2009-04-23)
Economic feasibility and sustainability of lignocellulosic ethanol production requires the development of robust microorganisms that can efficiently degrade and convert plant biomass to ethanol. The anaerobic thermophilic bacterium Clostridium thermocellum is a candidate microorganism as it is capable of hydrolyzing

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