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C7629

Sigma-Aldrich

L-Citrulline

≥98% (TLC)

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Synonym(s):
(S)-2-Amino-5-ureidopentanoic acid, L-2-Amino-5-ureidovaleric acid
Empirical Formula (Hill Notation):
C6H13N3O3
CAS Number:
Molecular Weight:
175.19
Beilstein/REAXYS Number:
1725416
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥98% (TLC)

form

powder

color

white to off-white

application(s)

detection

SMILES string

N[C@@H](CCCNC(N)=O)C(O)=O

InChI

1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1

InChI key

RHGKLRLOHDJJDR-BYPYZUCNSA-N

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This Item
A500627505748935
L-Citrulline ≥98% (TLC)

C7629

L-Citrulline

-
L-Arginine reagent grade, ≥98%

A5006

L-Arginine

Essential Grade
D-Citrulline ≥99.0%

27505

D-Citrulline

-
L-Citrulline-5-13C,4,4,5,5-d4 97 atom % D, 99 atom % 13C, 97% (CP)

748935

L-Citrulline-5-13C,4,4,5,5-d4

-
assay

≥98% (TLC)

assay

≥98%

assay

≥99.0%

assay

97% (CP)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

color

white to off-white

color

white

color

-

color

-

application(s)

detection

application(s)

cell analysis
peptide synthesis

application(s)

peptide synthesis

application(s)

-

Application

L-Citrulline has been used in ultra-performance liquid chromatography to validate, metabolites involved in the coordination of metamorphic processes.

Biochem/physiol Actions

Intermediate in the production of nitric oxide from L-arginine by NO synthetase.
L-Citrulline, when orally administered is found to ameliorate the condition of sickle cell disease in humans. L-citrulline can be a replacement for L-arginine administration in case of defective NO synthetase. L-Citrulline supplementation is found to fulfill the purpose of NO-dependent signaling.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Customers Also Viewed

l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Hayashi T
Proceedings of the National Academy of Sciences of the USA null
Nu-Hydroxy-L-arginine Is an Intermediate in the Biosynthesis of Nitric Oxide from L-Arginin
Dennis J. Stuehr
The Journal of Biological Chemistry, 266, 6259-6263 (1991)
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Schwedhelm E
British Journal of Clinical Pharmacology, 65(1), 51-59 (2008)
Ran Lin et al.
Molecular cell, 68(1), 198-209 (2017-10-07)
In addition to responding to environmental entrainment with diurnal variation, metabolism is also tightly controlled by cell-autonomous circadian clock. Extensive studies have revealed key roles of transcription in circadian control. Post-transcriptional regulation for the rhythmic gating of metabolic enzymes remains
Metabolomic insights into system-wide coordination of vertebrate metamorphosis.
Ichu TA
BMC Developmental Biology, 14:5, 1-24 (2014)

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