C8383

Sigma-Aldrich

Chloral hydrate

Synonym(s):
Trichloroacetaldehyde hydrate
Linear Formula:
Cl3CCH(OH)2
CAS Number:
Molecular Weight:
165.40
Beilstein/REAXYS Number:
1698497
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

assay

≥98% (titration)

drug control

USDEA Schedule IV

mp

57 °C (lit.)

SMILES string

OC(O)C(Cl)(Cl)Cl

InChI

1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H

InChI key

RNFNDJAIBTYOQL-UHFFFAOYSA-N

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Biochem/physiol Actions

Chloral hydrate is a sedative/hypnotic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

T

Risk Statement

25-36/38

Safety Statement

25-45

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Ya-Chen Ko et al.
Journal of anatomy, 214(1), 183-195 (2009-01-27)
CD200 is a highly glycosylated cell surface protein containing two immunoglobulin superfamily domains in the extracellular region and performs immunosuppressive activities. It is widely distributed in various tissues including the vascular endothelium. We report here the distribution of CD200 in...
Stephanie K West et al.
The British journal of ophthalmology, 97(11), 1437-1442 (2013-09-21)
To report the largest study on the safety and effectiveness of sedation in paediatric ophthalmology in a nurse-led outpatient sedation unit. Retrospective cohort study reviewing all children who underwent sedation from January 2006 to December 2010. Patients were sedated with...
Ya-Fen Jiang-Shieh et al.
Journal of anatomy, 216(3), 407-416 (2010-01-15)
In vivo and in vitro studies have clearly demonstrated that signaling mediated by the interaction of CD200 and its cognate receptor, CD200R, results in an attenuation of inflammatory or autoimmune responses through multiple mechanisms. The present results have shown a...
T L Sourkes
Molecular and chemical neuropathology, 17(1), 21-30 (1992-08-01)
Chloral hydrate was introduced into therapeutics more than 120 years ago, and soon became popular as a somnifacient. It is the first synthetic CNS depressant. Its metabolite, urochloralic acid, was detected early. Studies of the biochemical pharmacology of chloral hydrate...
J Silverman et al.
Laboratory animal science, 43(3), 210-216 (1993-06-01)
Chloral hydrate (CH) and alpha-chloralose (CS) are often used to anesthetize laboratory animals although, to our knowledge, there have been no controlled studies of their anesthetic or analgesic effects. Induction of and recovery from anesthesia can be stressful, and anesthesia...

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