C8383

Sigma-Aldrich

Chloral hydrate

Synonym(s):
Trichloroacetaldehyde hydrate
Linear Formula:
Cl3CCH(OH)2
CAS Number:
Molecular Weight:
165.40
Beilstein/REAXYS Number:
1698497
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (titration)

drug control

USDEA Schedule IV

mp

57 °C (lit.)

SMILES string

OC(O)C(Cl)(Cl)Cl

InChI

1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H

InChI key

RNFNDJAIBTYOQL-UHFFFAOYSA-N

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Biochem/physiol Actions

Chloral hydrate is a sedative/hypnotic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Stephanie K West et al.
The British journal of ophthalmology, 97(11), 1437-1442 (2013-09-21)
To report the largest study on the safety and effectiveness of sedation in paediatric ophthalmology in a nurse-led outpatient sedation unit. Retrospective cohort study reviewing all children who underwent sedation from January 2006 to December 2010. Patients were sedated with...
A D Steinberg
Pediatrics, 92(3), 442-446 (1993-09-01)
Current federal regulations of potentially carcinogenic environmental chemicals are based on the assumption that risks for humans can be extrapolated from the effects of chronic high-dose exposure of rodents. It is assumed that all chemicals induce cancer by a genotoxic...
T L Sourkes
Molecular and chemical neuropathology, 17(1), 21-30 (1992-08-01)
Chloral hydrate was introduced into therapeutics more than 120 years ago, and soon became popular as a somnifacient. It is the first synthetic CNS depressant. Its metabolite, urochloralic acid, was detected early. Studies of the biochemical pharmacology of chloral hydrate...
Simone Jürschik et al.
Journal of mass spectrometry : JMS, 47(9), 1092-1097 (2012-09-14)
In this work, we illustrate the application of proton transfer reaction mass spectrometry (PTR-MS) in the field of food and drink safety. We present proof-of-principle measurements of four different drinks (water, tea, red wine and white wine) each spiked separately...
Ya-Fen Jiang-Shieh et al.
Journal of anatomy, 216(3), 407-416 (2010-01-15)
In vivo and in vitro studies have clearly demonstrated that signaling mediated by the interaction of CD200 and its cognate receptor, CD200R, results in an attenuation of inflammatory or autoimmune responses through multiple mechanisms. The present results have shown a...

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