C8383

Sigma-Aldrich

Chloral hydrate

Synonym(s):
Trichloroacetaldehyde hydrate
Linear Formula:
Cl3CCH(OH)2
CAS Number:
Molecular Weight:
165.40
Beilstein/REAXYS Number:
1698497
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (titration)

drug control

USDEA Schedule IV

mp

57 °C (lit.)

SMILES string

OC(O)C(Cl)(Cl)Cl

InChI

1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H

InChI key

RNFNDJAIBTYOQL-UHFFFAOYSA-N

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Biochem/physiol Actions

Chloral hydrate is a sedative/hypnotic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

hazcat

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation

storage_class_code

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Jennifer Ngolab et al.
Acta neuropathologica communications, 8(1), 123-123 (2020-08-06)
An amendment to this paper has been published and can be accessed via the original article.
Ya-Chen Ko et al.
Journal of anatomy, 214(1), 183-195 (2009-01-27)
CD200 is a highly glycosylated cell surface protein containing two immunoglobulin superfamily domains in the extracellular region and performs immunosuppressive activities. It is widely distributed in various tissues including the vascular endothelium. We report here the distribution of CD200 in...
Stephanie K West et al.
The British journal of ophthalmology, 97(11), 1437-1442 (2013-09-21)
To report the largest study on the safety and effectiveness of sedation in paediatric ophthalmology in a nurse-led outpatient sedation unit. Retrospective cohort study reviewing all children who underwent sedation from January 2006 to December 2010. Patients were sedated with...
Megan M Monsanto et al.
Nature communications, 11(1), 3955-3955 (2020-08-10)
Cellular therapy to treat heart failure is an ongoing focus of intense research, but progress toward structural and functional recovery remains modest. Engineered augmentation of established cellular effectors overcomes impediments to enhance reparative activity. Such 'next generation' implementation includes delivery...
T L Sourkes
Molecular and chemical neuropathology, 17(1), 21-30 (1992-08-01)
Chloral hydrate was introduced into therapeutics more than 120 years ago, and soon became popular as a somnifacient. It is the first synthetic CNS depressant. Its metabolite, urochloralic acid, was detected early. Studies of the biochemical pharmacology of chloral hydrate...

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