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C8615

Sigma-Aldrich

CXCL16 human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):
CXC chemokine ligand 16
MDL number:
NACRES:
NA.75

biological source

human

Quality Level

recombinant

expressed in E. coli

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

2.5-12 ng/mL

mol wt

predicted mol wt ~10.1 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

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C8615

CXCL16 human

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E8399

Eotaxin-3 human

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized

potency

2.5-12 ng/mL

potency

0.25-1.0 mg

potency

0.1000 μg/mL

potency

-

mol wt

predicted mol wt ~10.1 kDa

mol wt

~8.2 kDa

mol wt

apparent mol wt 8.7 kDa by SDS-PAGE (reducing)

mol wt

11.2 kDa

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 1.25 mg bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to induce chemotaxis of mouse CXCR6 transfected BaF/3 cells.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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M Matloubian et al.
Nature immunology, 1(4), 298-304 (2001-03-23)
We describe a protein with the hallmarks of a chemokine, designated CXCL16, that is made by dendritic cells (DCs) in lymphoid organ T cell zones and by cells in the splenic red pulp. CXCL16 contains a transmembrane domain and both
Hina Mir et al.
Oncotarget, 6(12), 9985-9998 (2015-04-19)
Lung cancer (LuCa) is the leading cause of cancer-related deaths worldwide regardless of the gender. High mortality associated with LuCa is due to metastasis, molecular mechanisms of which are yet to be defined. Here, we present evidence that chemokine receptor

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