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C8890

Sigma-Aldrich

4-Chloro-1-naphthol

crystalline

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Synonym(s):
4-chloronaphthalen-1-ol
Linear Formula:
ClC10H6OH
CAS Number:
Molecular Weight:
178.61
Beilstein/REAXYS Number:
509750
EC Number:
MDL number:
PubChem Substance ID:

assay

≥98% (GC)

Quality Level

form

crystalline

mp

118-121 °C (lit.)

solubility

acetone: 50 mg/mL, clear, colorless to very faintly brown

storage temp.

−20°C

SMILES string

Oc1ccc(Cl)c2ccccc12

InChI

1S/C10H7ClO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H

InChI key

LVSPDZAGCBEQAV-UHFFFAOYSA-N

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1 of 4

This Item
C6788M2514N8141
vibrant-m

C8890

4-Chloro-1-naphthol

vibrant-m

C6788

4-Chloro-1-naphthol

vibrant-m

M2514

4-Methylumbelliferyl heptanoate

vibrant-m

N8141

4-Nitroquinoline N-oxide

solubility

acetone: 50 mg/mL, clear, colorless to very faintly brown

solubility

methanol: 10 mL, clear, colorless

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

solubility

acetone: soluble, clear to hazy

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

form

crystalline

form

tablet

form

powder

form

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mp

118-121 °C (lit.)

mp

118-121 °C (lit.)

mp

41-42 °C (lit.)

mp

154-156 °C (lit.)

Application

4-Chloro-1-naphthol has been used to visualize protein bands in western blotting. It has also been used in staining polyvinylidene fluoride (PVDF) membrane by Nakane method.

Biochem/physiol Actions

4-Chloro-1-naphthol serves as a substrate for horseradish peroxidase.

Substrates

Chromogenic peroxidase substrate useful in enzyme-linked detection procedures.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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A new sandwich-type impedimetric immunosensor based on functionalized graphene oxide nanosheets with a high ratio of horseradish peroxidase (HRP) and detection antibody was developed for the detection of carcinoembryonic antigen (CEA) by coupling with enzymatic biocatalytic precipitation of 4-chloro-1-naphthol (4-CN)

Articles

Nitroblue Tetrazolium (NBT) is used with the alkaline phosphatase substrate 5-Bromo- 4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures. These substrate systems produce an insoluble NBT diformazan end product that is blue to purple in color and can be observed visually.

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