This material is soluble in water at 50 mg/mL.
C9393
Cloxacillin sodium salt monohydrate
β-lactamase-resistant antibiotic
Synonym(s):
Cloxacillin, Sodium cloxacillin monohydrate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 g | Check Cart for Availability | $67.60 $50.70 | |
| 5 g | Check Cart for Availability | $272.00 |
About This Item
Linear Formula:
C19H17ClN3O5SNa · H2O
CAS Number:
Molecular Weight:
475.88
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
EC Number:
211-390-9
MDL number:
Quality Level
form
powder or crystals
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
O.[Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
InChI
1S/C19H18ClN3O5S.Na.H2O/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1
InChI key
KCUWTKOTPIUBRI-VICXVTCVSA-M
General description
Chemical structure: β-lactam
Application
Cloxacillin is effective against infections caused by penicillin G-resistant staphylococci. It was used in studies of topical antibacterial agents for burn and crush wounds.[1]
Biochem/physiol Actions
Cloxacillin is a semi-synthetic antibiotic and a chlorinated derivative of oxacillin. It inhibits the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cloxacillin is often used as AmpC β-lactamase inhibitor in combination with β-lactam antibiotics.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
1 of 1
This Item | |||
|---|---|---|---|
| antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes | mode of action cell wall synthesis | interferes |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder or crystals | form powder or crystals | form powder or crystals | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
Still not finding the right product?
Explore all of our products under Cloxacillin sodium salt monohydrate
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A New Antibacterial Agent: Sodium Cloxacillin Monohydrate (Tegopen)
Journal of the American Medical Association, 195, 569-570 (1966)
Srecko Marusic et al.
International journal of clinical pharmacology and therapeutics, 50(6), 431-433 (2012-06-09)
To present the case of warfarin-cloxacillin interaction that resulted in an increased international normalized ratio (INR). A 70-year-old man had been treated with warfarin for atrial fibrillation. He was hospitalized because of superficial thrombophlebitis of the left median cubital vein
Anna Stefánsdóttir et al.
Acta orthopaedica, 84(1), 87-91 (2013-02-16)
Prosthetic joint infections can be caused by bacteria derived from the patient's skin. The aim of the study was: (1) to determine which bacteria colonize the nose and groin in patients planned for primary hip or knee arthroplasty, (2) to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C9393-1G | 04061835506163 |
| C9393-5G | 04061835512362 |
-
In cosa può essere solubilizzata e a quale concentrazione massima?
1 answer-
Helpful?
-