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C9768

Sigma-Aldrich

DL-Cysteine hydrochloride

≥95% (TLC), anhydrous

Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
Molecular Weight:
157.62
Beilstein:
4150473
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

grade

anhydrous

assay

≥95% (TLC)

form

powder

application(s)

cell analysis: suitable
cell culture | mammalian: suitable

color

white

mp

109-112 °C

solubility

H2O: soluble

SMILES string

Cl.NC(CS)C(O)=O

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H

InChI key

IFQSXNOEEPCSLW-UHFFFAOYSA-N

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Application

DL-Cysteine hydrochloride is used in cell culture. It is also used in photochemical vascular injury (performed using dl-cysteine hydrochloride along with other components). It may be used in the preparation of DL-4-carboxy-3-formyl-2,2,-dimethylthiazolidine.

Biochem/physiol Actions

DL-Cysteine is a racemic mixture of the proteinogenic amino acids L-cysteine and the non-proteinogenic D-cysteine. DL-Cysteine is used as an organic reagent and in comparative physicochemical analysis of processes such as crystallization.
NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentration.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Katherine A Vousden et al.
Scientific reports, 9(1), 1605-1605 (2019-02-09)
Plasminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor (serpin) that regulates fibrinolysis, cell adhesion and cell motility via its interactions with plasminogen activators and vitronectin. PAI-1 has been shown to play a role in a number of diverse pathologies...
D W Young et al.
European journal of biochemistry, 75(1), 133-147 (1977-05-02)
1. (2R,3S)-[U-14C,3-3H1]- and (2R,3R)-[U-14C,2,3-3H2] Cysteine hydrochlorides have been separately synthesised. The latter compound has been shown to have uniform distributions of tritium between C-2 and C-3. 2. The abvoe cysteines and (2R)-[U-14C,3,3,3',3'-3H4]cystine have been converted to samples of penicillin G...
Sharlene M Day et al.
Circulation, 107(20), 2601-2606 (2003-05-07)
Iron overload has been implicated in the pathogenesis of ischemic cardiovascular events. However, the effects of iron excess on vascular function and the thrombotic response to vascular injury are not well understood. We examined the effects of chronic iron dextran...
Hiromi Hiruma et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(26), 8967-8977 (2003-10-03)
Impairment of axonal transport leads to neurodegeneration and synapse loss. Glutamate and amyloid beta-protein (Abeta) have critical roles in the pathogenesis of Alzheimer's disease (AD). Here we show that both agents rapidly inhibit fast axonal transport in cultured rat hippocampal...
Wenfeng Jiang et al.
Science (New York, N.Y.), 368(6491), 642-648 (2020-04-11)
The structural complexity of composite biomaterials and biomineralized particles arises from the hierarchical ordering of inorganic building blocks over multiple scales. Although empirical observations of complex nanoassemblies are abundant, the physicochemical mechanisms leading to their geometrical complexity are still puzzling...

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