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COV434

07071909

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Synonym(s):
COV-434 Cells

biological source

human ovary

growth mode

Adherent

karyotype

Modal chromosome no. 47 (46 - 47)

morphology

Polygonal & fusiform

products

Not specified

receptors

Not specified

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Related Categories

Cell Line Origin

Human ovarian granulosa tumour

Cell Line Description

Human ovarian granulosa tumour cell line established from a solid primary tumour.

Application

COV434 has been used to study:
  • the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
  • if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
  • the expression of TLR (toll-like receptor) and its function in the cell line

Culture Medium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

Subculture Routine

Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm2 using trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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