Cell Line Origin
Human Caucasian lung small cell carcinoma
Cell Line Description
This cell line has been established from the pleural fluid of a 55 year old Caucasian male with small cell carcinoma of the lung prior to treatment. Inoculated into athymic mice, the cells form tumours with a typical histology of the original biopsy specimen. Elevated levels of the biomarkers L-dopa decarboxylase, bombesin-like immunoreactivity, neuron-specific enolase and brain isozyme of creatine kinase were reported. Cells grow as spherical floating aggregates.
STR-PCR Data: Amelogenin: X,Y
RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Maintain cultures between 6x10,000 to 3x100,000 cells/ml; 5% CO2; 37°C.
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