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CHODHFR

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CHOZN® ZFN-Modified CHO Cell Line

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NACRES:
NA.75

description

CHOZN® DHFR-/- ZFN-modified CHO cell line
dihydrofolate reductase knockout cell line

Quality Level

shipped in

dry ice

storage temp.

−196°C

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CHOK1ZFNGSCHOGS
CHOZN® CHO K1 Host Cell Line Suspension-adapted in CD media

SAFC

CHOK1

CHOZN® CHO K1 Host Cell Line

storage temp.

−196°C

storage temp.

−196°C

storage temp.

−20°C

storage temp.

−196°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

description

CHOZN® DHFR-/- ZFN-modified CHO cell line

description

CHOK1 cell line derived from ECACC CHO K1

description

-

description

CHOZN® GS-/- ZFN-modified CHO cell line, glutamine synthetase knockout cell line

General description

CHOZN cell lines were created utilizing Sigma′s proprietary CompoZr Zinc Finger Nuclease (ZFN) technology to create genetic modifications in parental CHO-K1 cells. Cells are banked in chemically defined, animal component free EX-CELL CD CHO Fusion media

Cell Line Origin

CHOZN cell lines are all subclones of the parental CHO-K1 cell line originated by Puck in 1957.

Physical form

CHOZN cell lines are provided to customers in vials containing >7.5e6 cells/mL

Legal Information

All CHOZN cell lines are sold under license from Sigma Aldrich. A copy of the research license is provided with purchase of the CHOZN cell lines.
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Articles

MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.

In the present study, we have identifi ed species-specifi c housekeeping genes (HKGs) for Chinese Hamster Ovary (CHO) cells using data from microarray gene expression profiling.

A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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