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*We are so confident in the performance of our SygRNA® products, that we fully guarantee the quality and performance of any guide we produce, including custom sequences. If your SygRNA® guides do not yield detectable cleavage at the intended target site, we will provide you a one-time replacement, free of charge. To qualify for this guarantee, please send an image or sequencing data from a single experiment demonstrating detectable cleavage using one of our positive controls, side-by-side with the negative results from your SygRNA® guide.To receive your replacement, simply email us here and include sample data from a representative experiment (T7E1, TIDE, or NGS).
Your solution for screening the human and mouse whole genomes for drug discovery or target identification.
Order off-the-shelf KO gRNAs from the award-winning Sanger Whole Genome KO Arrayed CRISPR Libraries.
Synergistic Activation Mediators (SAM) are potent transcriptional activation protein complexes. The SAM CRISPRa system uses CRISPR-Cas9-mediated guidance to target SAM components to gene promoters, enabling site-specific transcriptional activation of a gene of interest.