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D1542

Sigma-Aldrich

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride

enzyme inhibitor

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Synonym(s):
2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride
Empirical Formula (Hill Notation):
C5H11NO3 · HCl
CAS Number:
Molecular Weight:
169.61
MDL number:
PubChem Substance ID:

Quality Level

assay

≥98% (TLC)

form

solid

storage condition

under inert gas

solubility

water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.OC[C@H]1NC[C@@H](O)[C@@H]1O

InChI

1S/C5H11NO3.ClH/c7-2-3-5(9)4(8)1-6-3;/h3-9H,1-2H2;1H/t3-,4-,5-;/m1./s1

InChI key

PZGVJCJRMKIVLJ-DEVUXVJFSA-N

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This Item
SAB2900066SAB2900042HPA000962
Gene Information

human ... PYGB(5834), PYGBL(5835), PYGL(5836), PYGM(5837)
mouse ... Gaa(14387), Glb1(12091), Treh(58866)
rat ... Man2a1(25478), Pygl(64035), Si(25588)

Gene Information

human ... PYGB(5834)

Gene Information

human ... PYGB(5834)

Gene Information

human ... PYGL(5836)

assay

≥98% (TLC)

assay

-

assay

-

assay

-

storage condition

under inert gas

storage condition

-

storage condition

-

storage condition

-

solubility

water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

Application

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

Biochem/physiol Actions

Inhibitor of glycogen phosphorylase and α-glucosidases.

Caution

Extremely hygroscopic, store and handle under argon

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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