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D184

Diethylamine NONOate sodium salt hydrate

≥97% (NMR), crystalline, nitrix oxide donor

Synonym(s):

1,1-Diethyl-2-hydroxy-2-nitroso-hydrazine sodium, 2-(N,N-Diethylamino)-diazenolate 2-oxide sodium salt hydrate, DEA NONOate sodium salt hydrate, Diethylamine/nitric oxide complex sodium salt hydrate

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$62.00

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About This Item

Linear Formula:
(CH3CH2)2N–N(N=O)O- Na+ xH2O
CAS Number:
1314960-89-8
Molecular Weight:
155.13 (anhydrous basis)
MDL number:
MFCD11045976
UNSPSC Code:
12352116
PubChem Substance ID:
24893276
NACRES:
NA.77

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Product Name

Diethylamine NONOate sodium salt hydrate, ≥97% (NMR)

Quality Level

100

assay

≥97% (NMR)

form

crystalline

storage condition

desiccated
protect from light

color

white

mp

45 °C (lit.)

solubility

H2O: >10 mg/mL
methanol: >25 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

O.[Na+].CCN(CC)N([O-])N=O

InChI

1S/C4H10N3O2.Na.H2O/c1-3-6(4-2)7(9)5-8;;/h3-4H2,1-2H3;;1H2/q-1;+1;

InChI key

BVCZSYKIXSAMOT-UHFFFAOYSA-N

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This Item
S7198N3139M3935
Diethylamine NONOate sodium salt hydrate ≥97% (NMR)

Sigma-Aldrich

D184

Diethylamine NONOate sodium salt hydrate

Sivelestat sodium salt hydrate ≥98% (HPLC), solid

Sigma-Aldrich

S7198

Sivelestat sodium salt hydrate

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate powder, BioReagent, suitable for cell culture

Sigma-Aldrich

N3139

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

Meloxicam sodium salt hydrate ≥98% (HPLC)

Sigma-Aldrich

M3935

Meloxicam sodium salt hydrate

form

crystalline

form

solid

form

powder

form

powder

assay

≥97% (NMR)

assay

≥98% (HPLC)

assay

≥98% (HPLC), ≥98% (spectrophotometric assay)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

solubility

H2O: >10 mg/mL, methanol: >25 mg/mL

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: 50 mg/mL

solubility

DMSO: 5 mg/mL, clear

storage condition

desiccated, protect from light

storage condition

-

storage condition

-

storage condition

-

Application

Diethylamine NONOate sodium salt hydrate has been used as a nitric oxide donor to evaluate endothelium-independent dilation.[1][2] It has also been used to determine the level of nitric oxide in cell free systems.[3]

Biochem/physiol Actions

Diethylamine NONOate is a complex of diethylamine with nitric oxide used to generate a controlled release of nitric oxide in solution.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000507055
0000507055
0000493070
0000493070
0000461201

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Nina Jeppesen Edin et al.
Journal of radiation research, 54(6), 1015-1028 (2013-05-21)
In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025)
Francesco Tamagnini et al.
The Journal of physiology, 591(16), 3963-3979 (2013-05-15)
Synaptic plasticity in perirhinal cortex is essential for recognition memory. Nitric oxide and endocannabinoids (eCBs), which are produced in the postsynaptic cell and act on the presynaptic terminal, are implicated in mechanisms of long-term potentiation (LTP) and long-term depression (LTD)
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson?s Disease Etiopathology
Wilkaniec A, et al.
Molecular Neurobiology, 56(1), 125-140 (2019)
Alice Miriam Kitay et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 44(4), 1606-1615 (2017-12-07)
L-arginine is an important mediator of cell division, wound healing, and immune function. It can be transformed by the nitric oxide synthase (NOS) to nitric oxide (NO), an important cell signaling molecule. Recent studies from our laboratory demonstrate specific effects
High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function
Toklu HZ, et al.
Journal of Physiology And Pharmacology, 67(2), 205-205 (2016)
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Articles

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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