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D5670

Sodium deoxycholate monohydrate

BioXtra, ≥99.0% (titration)

Synonym(s):

3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

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$1,130.00

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About This Item

Empirical Formula (Hill Notation):
C24H39NaO4 · H2O
CAS Number:
145224-92-6
Molecular Weight:
432.57
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24893956
EC Number:
206-132-7
Beilstein/REAXYS Number:
3643164
MDL number:
MFCD00150750

Key Documents

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InChI

1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/q;+1;/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI key

NDVHNZISGVSFMP-WTCAICSISA-M

description

anionic

product line

BioXtra

assay

≥99.0% (titration)

form

powder

optical activity

[α]20/D +44±2° in H2O(lit.)

mol wt

432.57 g/mol

technique(s)

electrophoresis: suitable, immunoprecipitation (IP): suitable

impurities

Insoluble matter, passes filter test, ≤0.5% Cholic acid

pH

7.5-9.5 (20 °C, 0.1 M in H2O)

solubility

H2O: 0.1 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.02%

cation traces

Al: ≤0.002%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.05%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.001%, K: ≤0.010%, Li: ≤0.0005%, Mg: ≤0.002%, Mn: ≤0.0005%, Mo: ≤0.0005%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.002%, Zn: ≤0.0005%

absorption

≤0.08 at 280 in H2O at 0.1 M, ≤0.10 at 260 in H2O at 0.1 M

Quality Level

200

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1 of 4

This Item
3096830970SRE0046
Sodium deoxycholate monohydrate BioXtra, ≥99.0% (titration)

Sigma-Aldrich

D5670

Sodium deoxycholate monohydrate

Sodium deoxycholate monohydrate BioUltra, ≥99.0% (NT)

Sigma-Aldrich

30968

Sodium deoxycholate monohydrate

Sodium deoxycholate BioXtra, ≥98.0% (dry matter, NT)

Sigma-Aldrich

30970

Sodium deoxycholate

Sodium deoxycholate Suitable for manufacturing of diagnostic kits and reagents

Sigma-Aldrich

SRE0046

Sodium deoxycholate

technique(s)

electrophoresis: suitable, immunoprecipitation (IP): suitable

technique(s)

-

technique(s)

DNA purification: suitable, RNA purification: suitable, electrophoresis: suitable

technique(s)

DNA purification: suitable, RNA purification: suitable, electrophoresis: suitable

form

powder

form

powder

form

powder

form

-

assay

≥99.0% (titration)

assay

≥99.0% (NT)

assay

≥98.0% (dry matter, NT)

assay

≥98% (HPLC)

anion traces

sulfate (SO42-): ≤0.02%

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤200 mg/kg

anion traces

-

anion traces

-

mol wt

432.57 g/mol

mol wt

average mol wt 1200-5000

mol wt

micellar avg mol wt 1200-5000

mol wt

micellar avg mol wt 1200-5000

product line

BioXtra

product line

BioUltra

product line

BioXtra

product line

-

General description

Sodium deoxycholate (SDC) monohydrate is a bile acid salt.

Application

Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.
Sodium deoxycholate monohydrate has been used in a study to assess a method for the immobilization of lipoxygenase in an alginate-silicate gel matrix. It has also been used in a study to investigate the in vitro dissolution of gall stones. [1]

Biochem/physiol Actions

Bile Salt

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000529983
0000529983
0000513922
0000513921
0000513922

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Immobilization of lipoxygenase in an alginate-silicate solgel matrix: formation of fatty acid hydroperoxides
Hsu, A., et al.
Biotechnology Letters, 19, 71-71 (1997)
Liquid crystals and phase equilibria binary bile salt-water systems.
Marques EF, et al.
Langmuir, 16(11), 5178-5186 (2000)
R P Modi et al.
Journal of the Indian Medical Association, 89(5), 129-132 (1991-05-01)
An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while
Effect of various lipid-bile salt mixed micelles on the intestinal absorption of amphotericin-B in rat
Dangi, J., et al.
Drug Devel. Ind. Pharm., 24, 631-631 (1998)
Suguru Yamasaki et al.
Scientific reports, 9(1), 177-177 (2019-01-19)
During infection, Salmonella senses and responds to harsh environments within the host. Persistence in a bile-rich environment is important for Salmonella to infect the small intestine or gallbladder and the multidrug efflux system AcrAB-TolC is required for bile resistance. The
View All Related Papers

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