All Photos(1)

D5946

Sigma-Aldrich

PD 150606

≥97% (HPLC)

All Photos(1)
Synonym(s):
(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Empirical Formula (Hill Notation):
C9H7IO2S
CAS Number:
179528-45-1
Molecular Weight:
306.12
MDL number:
MFCD00949076
PubChem Substance ID:
329798817
NACRES:
NA.77

Quality Level

100

assay

≥97% (HPLC)

form

powder

storage condition

protect from light

color

yellowish

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

SMILES string

OC(=O)\C(S)=C\c1ccc(I)cc1

InChI

1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-

InChI key

DJCVSFWGKYHMKH-YVMONPNESA-N

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

PD 150606 is a selective; cell-permeable; non-peptide; uncompetitive calpain inhibitor.

Pictograms

CorrosionSkull and crossbones
GHS05,GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

More documents

Structure Search
Bulk Quote-Order Product
Shuchen Hsieh et al.
Journal of nanoscience and nanotechnology, 9(5), 2894-2901 (2009-05-21)
Aminopropylsilatrane (AP-silatrane) was investigated as an adhesive layer for anchoring Au nanoparticles on silicon substrates. We compared the preparation procedure and film quality of the AP-silatrane films to those of 3-aminopropyltriethoxysilane (APTES), which is commonly used for nanoparticle attachment on...
Hong Wang et al.
Journal of inorganic biochemistry, 172, 16-22 (2017-04-19)
Calcium, as a ubiquitous second messenger, governs a large array of cellular processes and is necessary for cell survival. More recently, it was observed that the cytosolic Ca
Elina Välimäki et al.
Journal of immunology (Baltimore, Md. : 1950), 197(8), 3315-3325 (2016-09-18)
Extracellular ATP is an endogenous danger signal that is known to activate inflammatory responses in innate immune cells, including macrophages. Activated macrophages start to secrete proteins to induce an immune response, as well as to recruit other immune cells to...
Joel Selkrig et al.
Molecular systems biology, 17(2), e10188-e10188 (2021-02-17)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global threat to human health and has compromised economic stability. In addition to the development of an effective vaccine, it is imperative to understand how SARS-CoV-2 hijacks host cellular machineries...
Rosalie Heilig et al.
Life science alliance, 3(6) (2020-04-30)
Caspase-1 drives a lytic inflammatory cell death named pyroptosis by cleaving the pore-forming cell death executor gasdermin-D (GSDMD). Gsdmd deficiency, however, only delays cell lysis, indicating that caspase-1 controls alternative cell death pathways. Here, we show that in the absence...
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service