All Photos(1)

D7011

Sigma-Aldrich

Deoxyribonucleic acid sodium salt from human placenta

Type XIII

Synonym(s):
hpDNA, DNA
CAS Number:
MDL number:
NACRES:
NA.51

Quality Level

type

Type XIII

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Deoxyribonucleic acid (DNA) from placenta and its methylation pattern is indicative of anomalies in the fetal growth. Tobacco smoking during pregnancy favors methylation and epigenetic modulation of placental DNA.

Application

Deoxyribonucleic acid sodium salt from human placenta has been used:
  • as a standard for optimization of digestion followed by high-performance liquid chromatography (HPLC) and mass spectroscopy
  • as a standard for ultra violet (UV) spectrophotometer measurements
  • in polymerase chain reaction (PCR) assay and for standard curve generation for human papillomavirus type 6 quantification

Human placenta DNA (hpDNA) is a natural DNA used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Human placenta DNA is also used in physicochemical studies of DNA behavior in solution.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Results from the NIST 2004 DNA quantitation study
Kline MC, et al.
Journal of Forensic Sciences, 50(3), 1-8 (2005)
Genome-wide DNA methylation study in human placenta identifies novel loci associated with maternal smoking during pregnancy
Morales E, et al.
International Journal of Epidemiology, 45(5), 1644-1655 (2016)
Viral load and m RNA expression of HPV type 6 among cases with recurrent respiratory papillomatosis
Forslund O, et al.
Laryngoscope, 126(1), 122-127 (2016)
Johan S Nilsson et al.
Scientific reports, 9(1), 15432-15432 (2019-10-30)
Nasopharyngeal cancer (NPC) is associated with the Epstein-Barr virus (EBV). The clinical presentation and prognosis of NPC is well described, but not in relation to intralesional EBV-DNA load. In a retrospective design, 48 patients with NPC were examined. Patient history
DNA methylation in the human placenta and fetal growth
Koukoura O, et al.
Molecular Medicine Reports, 5(4), 883-889 (2012)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service