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MilliporeSigma

D7910

Sigma-Aldrich

3,4-Dichloroisocoumarin

serine protease inhibitor

Synonym(s):

3,4-DCI, 3,4-Dichloro-2-benzopyran-1-one

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5 MG
$241.30
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$465.00
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$1,010.00

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5 MG
$241.30
10 MG
$465.00
25 MG
$1,010.00

About This Item

Empirical Formula (Hill Notation):
C9H4Cl2O2
CAS Number:
Molecular Weight:
215.03
Beilstein/REAXYS Number:
6802625
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

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$241.30

List Price$254.00
Web-Only Promotion

In StockDetails


Technical Service
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Quality Level

assay

≥98% (TLC)

form

powder

solubility

ethyl acetate: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

ClC1=C(Cl)c2ccccc2C(=O)O1

InChI

1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H

InChI key

SUGXUUGGLDCZKB-UHFFFAOYSA-N

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This Item
E1379SML3559D104809
LAU-0901 ≥98% (HPLC)

SML3559

LAU-0901

assay

≥98% (TLC)

assay

≥99.45% (HPLC)

assay

≥98% (HPLC)

assay

99%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

form

powder

form

powder

form

powder

form

liquid

solubility

ethyl acetate: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

solubility

95% ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

DMSO: 2 mg/mL, clear

solubility

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

Application

Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.[1]

Other Notes

Effective concentration 5-100 μM.

Quantity

Half-life = 20 min at pH 7.5.

Substrates

Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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