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D9286

Sigma-Aldrich

Paraoxon-ethyl

≥90%, oil

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Synonym(s):
O,O-Diethyl O-(4-nitrophenyl) phosphate, Diethyl p-nitrophenyl phosphate, Paraoxon, Paraoxon-ethyl
Linear Formula:
O2NC6H4OP(O)(OC2H5)2
CAS Number:
Molecular Weight:
275.20
Beilstein/REAXYS Number:
1915526
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥90%

form

oil

color

yellow

refractive index

n20/D 1.51 (lit.)

density

1.274 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChI key

WYMSBXTXOHUIGT-UHFFFAOYSA-N

Gene Information

human ... PON1(5444)

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This Item
CRM494129310345607
Paraoxon-ethyl ≥90%, oil

D9286

Paraoxon-ethyl

Parathion certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

CRM49412

Parathion

Paraoxon-ethyl-d10 (diethyl-d10) PESTANAL®, analytical standard

93103

Paraoxon-ethyl-d10 (diethyl-d10)

Parathion PESTANAL®, analytical standard

45607

Parathion

form

oil

form

-

form

-

form

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

color

yellow

color

-

color

-

color

-

refractive index

n20/D 1.51 (lit.)

refractive index

-

refractive index

-

refractive index

-

density

1.274 g/mL at 25 °C (lit.)

density

-

density

-

density

-

Application

Paraoxon-ethyl has been used as a substrate in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein L3 (HDL3) to HDL2 in vivo.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Caution

air sensitive: handle under argon

Physical form

Oily liquid

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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