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  • D9641
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D9641

Sigma-Aldrich

Deoxygalactonojirimycin hydrochloride

Synonym(s):
1,5-Dideoxy-1,5-imino-D-galactitol, Migalastat
Empirical Formula (Hill Notation):
C6H13NO4 · HCl
CAS Number:
Molecular Weight:
199.63
MDL number:
PubChem Substance ID:
NACRES:
NA.32

biological source

synthetic (organic)

Quality Level

Assay

≥98% (HPLC)

form

powder or solid

solubility

water: soluble 1 mg/mL

storage temp.

−20°C

SMILES string

Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1

InChI key

ZJIHMALTJRDNQI-OLALXQGDSA-N

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USP

USP

1046089

N-Demethylazithromycin

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic

biological source

-

assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

≥99% (HPLC)

assay

-

form

powder or solid

form

powder

form

powder

form

-

solubility

water: soluble 1 mg/mL

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

Application

Deoxygalactonojirimycin hydrochloride has been used as an α-galactosidase A inhibitor to assess the enzymatic activity of α-galactosidase A. It has also been used as an α-galactosidase A inhibitor to study its effects on the mRNA levels in human embryonic kidney (HEK) cells and hippocampal neurons.

Biochem/physiol Actions

Deoxygalactonojirimycin hydrochloride is an inhibitor of α-galactosidase A. Deoxygalactonojirimycin exhibits therapeutic effects against Fabry disease.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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